Aldol reaction - Wikipedia, the free encyclopedia
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The aldol reaction is a powerful means of forming carbon-carbon bonds in organic chemistry. Discovered independently by Charles-Adolphe Wurtz and Alexander Porfyrevich Borodin in 1872, the reaction ...
en.wikipedia.org/wiki/Aldol_reaction
Aldol condensation - Wikipedia, the free encyclopedia
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An Aldol condensation is an organic reaction in which an enolate ion reacts with a carbonyl compound to form a β-hydroxyaldehyde or β-hydroxyketone, followed by dehydration to give a conjugated enon...
en.wikipedia.org/wiki/Aldol_condensation
The Aldol Reaction ... The Aldol Reaction of Acetaldehyde ... General Features of the Aldol Reaction...
usm.maine.edu/~newton/Chy251_253/Lectures/Aldol%20Conde... usm.maine.edu/~newton/Chy251_253/Lectures/Aldol%20Condensation/AldolReaction.html
; Highly Enantioselective Organocatalytic Direct Aldol Reaction in an Aqueous Medium; V. Maya, M. Raj, V. K. Singh, Org. Lett., 2007, 9, 2593-2595. ... The First Direct and Enantioselective Cross-Aldol Reaction of Aldehydes; A. B. Northtrup, D. W. C. MacMillan, J. Am. Chem. Soc., 2002, 124, 6798-6799.
www.organic-chemistry.org/namedreactions/aldol-addition... www.organic-chemistry.org/namedreactions/aldol-addition.shtm
BINAP/AgOTf/KF/18-Crown-6 as New Bifunctional Catalysts for Asymmetric Sakurai-Hosomi Allylation and Mukaiyama Aldol Reaction; M. Wadamoto, N. Ozasa, A. Yanagisawa, H. Yamamoto, J. Org. Chem., 2003, 68, 5593-5601.
www.organic-chemistry.org/namedreactions/mukaiyama-aldo... www.organic-chemistry.org/namedreactions/mukaiyama-aldol-addition.shtm
In the presence of acid or base catalysts the aldol reaction is reversible, and the beta-hydroxy carbonyl products may revert to the initial aldehyde or ketone reactants. In the absence of such catalysts these aldol products are perfectly stable and isolable compounds.
www.cem.msu.edu/~reusch/VirtualText/aldket2.htm
The method is compromised by self-condensation, polycondensation, generation of regioisomeric enols/enolates, and dehydration of the aldol followed by Michael addition, q.v. The development of methods for the preparation ... Henry Reaction; Ivanov Reaction; Knoevenagel Condensation; Reformatsky Reaction; Robinson Annulation.
themerckindex.cambridgesoft.com/TheMerckIndex/NameReact... themerckindex.cambridgesoft.com/TheMerckIndex/NameReactions/displayonr.asp?onr=ONR004.htm
The Aldol Reaction ... The Aldol Reaction of Acetaldehyde ... General Features of the Aldol Reaction...
www.usm.maine.edu/~newton/Chy251_253/Lectures/Aldol%20C... www.usm.maine.edu/~newton/Chy251_253/Lectures/Aldol%20Condensation/AldolFS.html
Hemiacetals, Acetals and the Aldol Reaction (2/7/96) ... The next reaction (the aldol reaction) we'll look at is one which makes a carbon-carbon bond. Such reactions are important in many contexts. One example is the photosynthetic conversion of CO2 to glucose, C6H12O6.
dwb.unl.edu/Teacher/NSF/C10/C10Links/www.chem.wsu.edu/c... dwb.unl.edu/Teacher/NSF/C10/C10Links/www.chem.wsu.edu/chem102/102-AcetalAldol.html
The simplest aldol reaction is the condensation of ethanal. This is shown below in 2 different representations (the line diagrams are less cluttered)..... ... Recognise the products, either the b-hydroxyaldehydes = the aldol, or the conjugated product, the enal as being from an Aldol reaction.
www.chem.ucalgary.ca/courses/351/Carey/Ch18/ch18-3-4.ht... www.chem.ucalgary.ca/courses/351/Carey/Ch18/ch18-3-4.html