Definition and other additional information on Anchorage dependence from Biology-Online.org dictionary. ... Loss of anchorage dependence seems to be associated with greater independence from external growth control and is probably one of the best correlates of tumourigenicity in vivo.
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Definition of anchorage dependence from the online medical dictionary hosted by mondofacto. ... A loss of contact or anchorage-dependence is associated with malignant cells, and abscence of anchorage-dependence can be detected by growing cells in soft agar or in suspension, as those cells that are anchorage-dependent will...
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To evaluate the pathway regulating the anchorage dependence of ERK2 activation, we used a dominant-negative mutant of p21-activated kinase (PAK) and a specific inhibitor (H89) of cAMP-dependent protein kinase (PKA) because PAK and PKA are known to regulate the anchorage dependence of ERK2 activation.
www.medscape.com/medline/abstract/11825889
The Medscape Journal ... Allergy & Clinical Immunology ... Diabetes & Endocrinology...
www.medscape.com/medline/abstract/8454583
Cytokines & Cells Online Pathfinder Encyclopaedia ... Most normal cells derived from solid animal tissues are anchorage-dependent and show a finite life span. Loss of anchorage dependence is usually a sign of cell transformation.
www.copewithcytokines.de/cope.cgi?key=Anchorage-depende... www.copewithcytokines.de/cope.cgi?key=Anchorage-dependent%20cells
Anchorage dependence of growth - the role of the cytoskeleton ... This is anchorage dependence of growth, a control to cell division that many transformed cells loose. The ability to grow on "soft agar" is a routine test taken as an indication that cells with this ability are anchorage independent (see below).
www.bms.ed.ac.uk/research/others/smaciver/Cell%20biol.t... www.bms.ed.ac.uk/research/others/smaciver/Cell%20biol.topics/anchorage_dependence_of_growth.htm
The reduced need for growth factors may be responsible for the lack of contact inhibition and anchorage dependence discussed above. ... Lack Anchorage Dependence...
faculty.clintoncc.suny.edu/faculty/michael.gregory/file... faculty.clintoncc.suny.edu/faculty/michael.gregory/files/Bio%20101/Bio%20101%20Lectures/cancer/cancer.htm
Anchorage dependence defines the cellular requirement for integrin-mediated adhesion to substrate to initiate DNA replication in response to growth factors.
www.jimmunol.org/cgi/content/full/162/9/5085
Characterization of Integrin and Anchorage Dependence in Mammary Epithelial Cells following c-erbB2-Induced Epithelial-Mesenchymal Transition; Lachmi E. Jenndahla, Joyce Taylor-Papadimitrioub, Dan Baeckströma;
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ANCHORAGE DEPENDENCE: Review the definition, meaning, pronunciation, explanation, synonyms, and antonyms of the term ANCHORAGE DEPENDENCE in the Online Dictionary. ... English Dictionary Computer Dictionary Video Dictionary Thesaurus Dream Dictionary Medical Dictionary ... Only transformed cells, hybridomas and hematopoietic...
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