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Aromatase - Wikipedia, the free encyclopedia
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Aromatase inhibitor - Wikipedia, the free encyclopedia
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ERDs in breast cancer treatment ... Aromatase inhibitors stop the production of estrogen in post-menopausal women. Aromatase inhibitors work by blocking the enzyme aromatase, which turns another enzyme, androgen, into small amounts of estrogen in the body.
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SAN ANTONIO -- High-dose vitamin D significantly reduced mucle and joint pain in breast cancer patients treated with the aromatase inhibitor anastrozole (Arimidex), results of a small, randomized clin ... Musculoskeletal pain is a class adverse effect of aromatase inhibitors. The St. Louis group previously had reported a...
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Manipulating the function of hormones, particularly estrogen has long been a useful tool in treating breast cancer... In postmenopausal women, the ovaries no longer makes estrogen, and the body's main source of estrogen is the conversion of androgens, which are produced primarily in the adrenal glands. ... In the 70's and 80's,
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Two other aromatase inhibitors, letrozole and exemestane, are also proving more effective than tamoxifen. ... "In metastatic disease, and possibly in the adjuvant setting as well, it appears that the aromatase inhibitors will replace tamoxifen, at least for postmenopausal women," says Lawrence Wickerham, MD,
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