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Autocrine signalling - Wikipedia, the free encyclopedia
Autocrine signaling is a form of signaling in which a cell secretes a hormone or chemical messenger (called the autocrine agent) that binds to autocrine receptors on the same type of cell , leading...
en.wikipedia.org/wiki/Autocrine_signalling |
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Paracrine signalling - Wikipedia, the free encyclopedia
Paracrine signaling is a form of cell signaling in which the target cell is near ("para" = near) the signal-releasing cell. A distinction is sometimes made between paracrine and autocrine signaling. ...
en.wikipedia.org/wiki/Paracrine_signalling |
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Endocrine system - Wikipedia, the free encyclopedia
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The cooperation of autocrine PDGFR signaling with oncogenic Ras hyperactivates PI3K and is required for survival during EMT. Autocrine PDGFR signaling also contributes to maintenance of EMT, possibly through activation of STAT1 and other distinct pathways.
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The Hedgehog (Hh) family of signaling molecules functions in the development of numerous tissues during embryogenesis and has also been involved in adult self-renewing tissues. ... Taken together, these results suggest that the survival and function of thymic DCs are regulated by an autocrine Hh signaling.
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We propose that autocrine growth signaling pathways distinct from EGFR are active in NSCLC cells. To this end, gene expression profiling revealed frequent coexpression of specific fibroblast growth factors (FGFs) and FGF receptors (FGFRs) in NSCLC cell lines.
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Autocrine signaling systems are commonly studied under cell culture conditions. In a typical cell culture assay, a layer of liquid medium covers a random two-dimensional dispersion of cells, which secrete ligands.
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