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click on the picture above to interact with the 3D model of the; AZT structure ; (this will open a new browser window) ... Zidovudine or azidothymidine (AZT) is an antiretroviral drug, the first approved for treatment of HIV. Zidovudine was the first drug approved for the treatment of AIDS and HIV infection.
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www.3dchem.com/moremolecules.asp?ID=340&othername=AZT
www.3dchem.com/moremolecules.asp?ID=340&othername=AZT
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Zidovudine - Wikipedia, the free encyclopedia
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Zidovudine (INN) or azidothymidine ( AZT ) (also called ZDV) is a nucleoside analog reverse transcriptase inhibitor (NRTI), a type of antiretroviral drug. It was the first approved treatment for ...
en.wikipedia.org/wiki/Zidovudine
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1. The structure of AZT, a drug used with some success in the treatment of AIDS, is shown below. ... (a) The condensed formula of AZT is C10H13N5O4. ... (e) Indicate the configuration of all of the stereocenters in (+)-AZT on the structure given above.
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www.chemistry.mcmaster.ca/~chem2o6/problems/97ansmt1.ht...
www.chemistry.mcmaster.ca/~chem2o6/problems/97ansmt1.html
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In order to better understand the structural details of AZT resistance, we solved the 3.0 A crystal structure of an RT:dsDNA complex that is the substrate for the excision reaction: The primer strand of the nucleic acid duplex has been blocked by AZTMP and covalently trapped so that the primer terminus does not...
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gateway.nlm.nih.gov/MeetingAbstracts/102249612.html
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The AZT structure was built manually using drawing tools and subjected to geometrical optimization. RESULTS AND DISCUSSION ...
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www.liebertonline.com/doi/pdf/10.1089/10445490432296472...
www.liebertonline.com/doi/pdf/10.1089/104454904322964724
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Based on the 1H and 13C NMR data of the studied AZT biotransformation product, one can suggests that its structure is very similar to the AZT structure [9 ...
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linkinghub.elsevier.com/retrieve/pii/S0022286003001182
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Assessing AZT from its structure, ... For √OH, the implicating groups in the AZT structure (Fig. ...
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linkinghub.elsevier.com/retrieve/pii/S0306987702001469
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24 Hour Shipping on most orders. AZT Molecule (card) created by Derethman. This design is available in several sizes and is totally customizable. ... Tags: Chemistry, Molecule, AZT, irving; Store Category: Chemistry Products;
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www.zazzle.com/product/137309975443009150
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The research suggests that AZT, an agent in the class of drugs called thymidine analogs, is less effective than it might be due to a fundamental flaw in its chemical structure. This flaw prevents AZT from being efficiently metabolized in the body.
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www.thebody.com/napwa/aztflaw.html
www.thebody.com/napwa/aztflaw.html
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