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Problems with integrating therapeutic DNA into the genome and the rapidly dividing nature of many cells prevent gene therapy from achieving any long-term benefits. Patients will have to undergo multiple rounds of gene therapy.
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www.ornl.gov/sci/techresources/Human_Genome/medicine/ge...
www.ornl.gov/sci/techresources/Human_Genome/medicine/genetherapy.shtml
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In the first week of October 2002, the French Medicine Agency (AFSSAPS) announced that the clinical trial of gene therapy led by Professors Marina Cavazzana-Calvo and Alain Fischer for patients with X-linked severe combined immunodeficiency (X-SCID) had been voluntarily suspended.
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www.nature.com/gt/journal/v9/n23/full/3301924a.html
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The potential of gene therapy is great but, compared to its promise, the results to date are still quite limited. However, the benefits of gene therapy are believed to be on the near horizon. Gene therapy is one of the hottest areas of medical research today.
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www.medicinenet.com/script/main/art.asp?articlekey=1266...
www.medicinenet.com/script/main/art.asp?articlekey=12662&page=2
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Against a backdrop of genetic ‘hype’, secrecy, the privatisation of basic knowledge and profit-driven motives, the benefits of gene therapy may not only be more elusive than predicted, they may also be restricted to the few who can afford them.
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www.twnside.org.sg/title/twr127b.htm
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Perspective from The New England Journal of Medicine -- Risks and Benefits of Gene Therapy ... Risks and Benefits of Gene Therap ... Although most of today's gene-therapy trials are targeted to cancer, there is renewed interest in pursuing the goal for which gene therapy was invented: the cure of genetic disease.
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content.nejm.org/cgi/doi/10.1056/NEJMp020184
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What is Gene Therapy? ... Examples of Gene therapy ... Disadvantages of Gene Therapy...
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www.ndsu.nodak.edu/instruct/mcclean/plsc431/students/br...
www.ndsu.nodak.edu/instruct/mcclean/plsc431/students/brandi.htm
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It was also found that analgesics do not cause hypertension in men (in contradistinction to last month's report in women), whereas antihypertensive medications prevent headaches. Finally is gene therapy for hypertension on the horizon? ... Significant New Definitions, Publications, Risks, Benefits -- and Gene Therapy?
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www.medscape.com/viewarticle/514644
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BOSTON (Reuters) - A year after receiving gene therapy for a condition that causes total blindness by age 30, three people continue to see better and one has improved enough to read the digital numbers on the clock in her parents' car, U.S. researchers said on Wednesday.
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www.reuters.com/article/scienceNews/idUSTRE57B5PN200908...
www.reuters.com/article/scienceNews/idUSTRE57B5PN20090812
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