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Cooking Up Biological Plausibility ... Earlier we said biological plausibility is an essential element of the epidemiology equation. If your statistical association doesn't make some sort of biological sense, you're in trouble.
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www.junkscience.com/news/sws/sws-chapter9.html
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Although population-based studies have unequivocally reported an increased risk of ovarian cancer in women with endometriosis, the biological evidence supporting the idea of endometriosis as a preneoplastic condition is scanty and not well substantiated.
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humupd.oxfordjournals.org/cgi/content/abstract/12/1/77
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Automatic download; [Begin manual download] ... Downloading the PDF version of:; Hum Reprod Update Viganó et al. 12 (1): 77. (138K) ... This file is in Adobe Acrobat (PDF) format. If you have not installed and configured the Adobe Acrobat Reader on your system, see Help with Printing for instructions.
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humupd.oxfordjournals.org/cgi/reprint/12/1/77
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Biological plausibility. The association should be coherent; that is, plausible and explicable biologically according to known facts in the natural history and biology of the disease. ... The requirement for biological plausibility should not unduly influence negatively a consideration of causality.
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www.who.int/entity/vaccine_safety/causality/en/
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Title BIOLOGICAL PLAUSIBILITY ... Document Date 19920000/E ... Document Type REPT, REPORT, OTHER ; BIBL, BIBLIOGRAPHY...
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legacy.library.ucsf.edu/tid/wfk02a00
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What is most important to reiterate is that the causes of health and disease are generally viewed as a product of the interplay or interaction between biological, ... Biological plausibility is often established in animal models of disease. That is why researchers seek animal models in which to study causation.
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www.surgeongeneral.gov/library/mentalhealth/chapter2/se...
www.surgeongeneral.gov/library/mentalhealth/chapter2/sec3.html
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“Our cardiology fellows have a bulletin board,” Nissen replied, “and there’s a quote from me that’s prominently displayed. And the quote says the road to hell is paved with biological plausibility.”...
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www.pharmalot.com/2008/07/the-road-to-hell-is-paved-wit...
www.pharmalot.com/2008/07/the-road-to-hell-is-paved-with-biological-plausibility/
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We briefly mentioned in the Modeling Cortical ... sectionabout possible relations between the lateral connections in our model and the horizontal connections in the visual cortex. ... It is known that the horizontal connections originate from pyramidal cells, ... Although the horizontal connections can span quite a long range,
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nn.cs.utexas.edu/web-pubs/htmlbook96/wang/node10.html
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Biological plausibility is helpful, however. A biologically plausible mechanism of action greatly aids the investigator in selecting an appropriate dosing regimen and patient population, and encourages persistence in the face of disappointing results.
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www.cmaj.ca/cgi/content/full/168/2/180
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