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A large number of diseases are associated with abnormally increased or decreased levels of calcitonin, but pathologic effects of abnormal calcitonin secretion per se are not generally recognized.
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arbl.cvmbs.colostate.edu/hbooks/pathphys/endocrine/thyr...
arbl.cvmbs.colostate.edu/hbooks/pathphys/endocrine/thyroid/calcitonin.html
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A normal value is less than 10 pg/ml (picograms per milliliter). Note: Normal ranges may differ by the laboratory of the health care provider; it is not uncommon to see different normal values for males and females. Sometimes, health care ...
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www.nlm.nih.gov/medlineplus/ency/article/003699.htm#Nor...
www.nlm.nih.gov/medlineplus/ency/article/003699.htm#Normal%20Values
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Calcitonin levels may be ordered when you are suspected of having C-cell hyperplasia or medullary thyroid cancer. You or your doctor may notice a lump or swelling at the front of your neck. You may also experience other symptoms such as:
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www.labtestsonline.org/understanding/analytes/calcitoni...
www.labtestsonline.org/understanding/analytes/calcitonin/test.html
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In this case, post operative calcitonin levels will go to zero. This is often not the case, and calcitonin levels remain elevated, but less than pre-operatively. These levels should still be checked every 6 months, and when they begin to rise, a more diligent examination is in order to find the source.
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www.endocrineweb.com/camed.html
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Medullary thyroid carcinoma (MTC) is a calcitonin (CT)-secreting endocrine tumor. Although plasma CT level is a specific and sensitive marker of MTC, its preoperative usefulness in ... Furthermore, preoperative CT levels under 50 pg/mL appeared to be predictive of postoperative CT normalization (44 of 45 patients).
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www.medscape.com/medline/abstract/10690910
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The effects of aging on calcitonin (CT) secretion in female rats were investigated. Old (24 mo) at constant diestrus status and young (2 mo) at diestrus status ... The basal and post-CaCl2 levels of plasma Ca measured with radioimmunoassay were significantly higher (P less than 0.05-0.01) in old than in young female rats.
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www.medscape.com/medline/abstract/1590367
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Occasionally some patients will also have diarrhea, possibly due to the elevated calcitonin levels in the blood produced by the tumor. Sometimes people with the hereditary form for medullary thyroid cancer have hypertension, increased heart rate, headaches and/or other endocrine disease.
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www.cumc.columbia.edu/dept/thyroid/medullary.html
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High calcitonin levels may also be seen in a few other tumors. Small cell lung cancer is one example. Carcinoembryonic antigen may also be elevated in medullary carcinoma. Elevation of CEA is a poor prognostic factor, as it correlates with the presence of distant metastasis.
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www.bcm.edu/oto/grand/072299.html
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Calcitonin levels are correlated with age and BMI (especially in men). Cigarette smoking can increase the concentration of CT, and so taking this factor into account will help interpret moderately elevated CT levels, especially in men.
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www.eje-online.org/cgi/reprint/157/6/749.pdf
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