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Canalisation (genetics) - Wikipedia, the free encyclopedia
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Canalization - Wikipedia, the free encyclopedia
Canalization may refer to: •Channelization, the process of modifying the course of a stream so that it follows a restricted path • In River engineering the process of introducing weirs and locks to a...
en.wikipedia.org/wiki/Canalization |
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Animal development is an extremely robust process resulting in stereotyped outcomes. ... Canalization is a design principle wherein developmental pathways are stabilized to increase phenotypic reproducibility. Recent revelations into microRNA (miRNA) function suggest that miRNAs act as key players in canalizing genetic programs.
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Waddington's canalization revisited: developmental stability and evolution. ... It has been claimed that this robustness, termed canalization, evolves because of long-term natural selection for optimal phenotypes. ... The extent of canalization, measured as the insensitivity to mutation of a network's equilibrium state,
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Canalization is a design principle wherein developmental pathways are stabilized to increase phenotypic reproducibility. Recent revelations into microRNA (miRNA) function suggest that miRNAs act as key players in canalizing genetic programs.
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We propose a mathematical model to analyze the evolution of canalization for a trait under stabilizing selection, where each individual in the population is randomly exposed to different environmental conditions, independently of its genotype.
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