Cachexia - Wikipedia, the free encyclopedia
Cachexia (pronounced /kəˈkɛksiə/ ) is loss of weight, muscle atrophy, fatigue, weakness and significant loss of appetite in someone who is not actively trying to lose weight. The formal definit...
en.wikipedia.org/wiki/Cachexia
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Cancer cachexia describes a syndrome of progressive weight loss, anorexia, and persistent erosion of host body cell mass in response to a malignant growth. ... Because of metabolic derangements seen in cancer cachexia, effective nutritional treatment regimens will probably require manipulation of host intermediary...
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www.ncbi.nlm.nih.gov/pubmed/3292798
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A number of therapeutic agents for cancer cachexia have been investigated in the recent past. However, most studies are limited to a single tumor type and may or may not be applicable to all patients suffering from this condition.
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www.oncolink.org/resources/article.cfm?c=3&s=38&ss=164&...
www.oncolink.org/resources/article.cfm?c=3&s=38&ss=164&id=828
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Bing C et al. (2000) Increased gene expression of brown fat uncoupling protein (UCP)1 and skeletal muscle UCP2 and UCP3 in MAC16-induced cancer cachexia. Cancer Res 60: 2405-2410...
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www.medscape.com/viewarticle/502423
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PURPOSE: Previous double-blind, placebo-controlled, randomized clinical trials have demonstrated that both corticosteroids and progestational agents do partially alleviate cancer anorexia/cachexia. ... PATIENTS AND METHODS: Patients suffering from cancer anorexia/cachexia were randomized to receive either dexamethasone 0.
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www.medscape.com/medline/abstract/10506633
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Cancer cachexia occurs most frequently in malignancy and is associated with more than 20% of cancer deaths [1]. Patients with upper gastrointestinal cancer are especially likely to suffer from substantial weight loss, and patients with pancreatic cancer have the highest frequency of developing a cachectic syndrome.
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www.molecular-cancer.com/content/2/1/36
www.molecular-cancer.com/content/2/1/36
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Patients with cancer cachexia show a progressive loss of body weight, which is mainly due to loss of fat and skeletal muscle. Survival of cancer patients is directly related to the total weight loss and also the rate of weight loss.
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www.annieappleseedproject.org/cacincanpat.html
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Cancer cachexia is a wasting syndrome in which fat and muscle are lost because of the presence of a tumor. Patients lose weight and appetite, and become weak and tired. Even when nutrition is adequate, skeletal muscle breakdown occurs, along with abnormal fat and carbohydrate metabolism.
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www.aafp.org/afp/20040215/tips/21.html
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Cancer cachexia results in severe wasting of muscle and connective tissue and is one of the most common debilitating and distressing conditions of advanced cancer. Severe cachexia is associated with extreme weakness, intolerance to chemotherapy and substantially reduced life expectancy.
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www.medicalnewstoday.com/articles/60909.php
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