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True hypoplasia is a developmental phenomenon whose cause is a little hard to pinpoint. Any systemic distrubance over a long period of time can effect developing tooth enamel.
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cyberdentist.blogspot.com/2006/08/white-spots-on-teeth-...
cyberdentist.blogspot.com/2006/08/white-spots-on-teeth-enamel-hypoplasia.html
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Tooth enamel - Wikipedia, the free encyclopedia
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Tooth enamel is the hardest and most highly mineralized substance of the body, and with dentin, cementum, and dental pulp is one of the four major tissues which make up the tooth in vertebrates. Toot...
en.wikipedia.org/wiki/Tooth_enamel
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The biochemical cause of enamel hypoplasia is not fully understood, but growing evidence indicates it is strongly linked to calcium homeostasis.[1] There are several studies that suggest a direct relationship between enamel hypoplasia in primary teeth and neonatal hypocalcemia.[2,8] There are numerous pre- and...
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www.medscape.com/viewarticle/461574_3
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Ageneses Enamel, Agenesis Enamel, DENT ENAMEL HYPOPLASIA, Dental Enamel Hypoplasia, Enamel Ageneses, Enamel Agenesis, Enamel hypoplasia, Enamel hypoplasia (disorder), ENAMEL HYPOPLASIA DENT, Enamel Hypoplasia Dental, Enamel Hypoplastic, enamel of teeth hypoplasia, HYPOPLASIA DENT ENAMEL,
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en.diagnosispro.com/free/search_results/?q=Teeth+enamel...
en.diagnosispro.com/free/search_results/?q=Teeth+enamel+hypoplastic&w=7
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Systemic postnatal infections (eg, measles, chicken pox, streptococcal infections, scarlet fever) can also cause enamel hypoplasia. The bandlike discolorations on the tooth are visualized where the enamel layer has variable thickness and becomes extrinsically stained after tooth eruption.
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emedicine.medscape.com/article/1076389-overview
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In many cases, the exact cause of enamel hypoplasia cannot be determined. ... Most cases of enamel hypoplasia occur before the age of three. Any trauma occurring after this time is less likely to cause enamel defects. This is because the tooth enamel is already calcified and more resistant to traumatic factors.
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www.wisegeek.com/what-is-enamel-hypoplasia.htm
www.wisegeek.com/what-is-enamel-hypoplasia.htm
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Systemic syndromes often cause enamel hypoplasia (inadequate development) and pitting of the enamel. ... In cases of enamel hypoplasia, the development of the tooth germ was disturbed by trauma, infection, or systemic disturbance.
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dentalresource.org/topic53stainedteeth.html
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Furthermore, the patients did not show any systemic disease which could cause general enamel hypoplasia, such as renal or endocrine disturbances involving calcium metabolism (Seow, 1993). The morphological pattern of the enamel and the family distribution characteristics are in keeping with the genetic anomaly known...
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www.forp.usp.br/bdj/bdj10(2)/t08102/t08102.html
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[Clinical study of enamel hypoplasia and its causes. 1. Primary teeth] ... The controls consisted of 120 children without enamel hypoplasia. The following results were obtained: 1. Hypoplastic teeth due to inflammation, trauma or radiation were not found.
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www.ncbi.nlm.nih.gov/pubmed/2133959
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