|
Collagen is a protein found abundantly throughout the bodies of animals, including humans. In fact, collagen makes up about one-third of the total body weight. Collagen is an important component of the body's connective tissues, which perform a variety of functions in the body.
|
science.jrank.org/pages/1584/Collagen.html
science.jrank.org/pages/1584/Collagen.html
|
|
|
|
Collagen is a primary component of the connective tissue located in the dermis, the tough inner layer of the skin. This kind of connective tissue is also found in mucous membranes, nerves, blood vessels, and organs.
|
science.jrank.org/pages/1582/Collagen-Locations-functio...
science.jrank.org/pages/1582/Collagen-Locations-functions-collagen.html
|
|
|
Collagen cross-linking was inhibited by treating five normal adult pigs with beta-aminopropionitrile (BAPN; 10 g/day po) for 6 wk; five normal untreated pigs served as controls. Left ventricular volume, mass, and function were determined by simultaneous echocardiography and catheterization.
|
www.medscape.com/medline/abstract/7573529
|
|
If too much collagen is deposited in the wound site, normal anatomical structure is lost, function is compromised, and the problem of fibrosis results. Conversely, if insufficient amounts of collagen are deposited, the wound is weak and may dehisce.
|
www.medscape.com/viewarticle/423231
|
|
15 Collagen structure-function relations (cont.) The architectural structure of collagen determines the function of collagen fibers as mechanical reinforcements of connective tissues (tendon, skin, bone, arteries etc.). Tendon fibers are bundles of uniaxially aligned fibers that are crimped.
|
ocw.mit.edu/NR/rdonlyres/FD81BAAF-3919-49EF-9ABA-CC348E...
ocw.mit.edu/NR/rdonlyres/FD81BAAF-3919-49EF-9ABA-CC348EF3FC7F/0/l5_collagen.pdf
|
|
Dystrophic epidermolysis bullosa (DEB) is a family of inherited mechano-bullous disorders that are caused by mutations in the type VII collagen gene and for which ex vivo gene therapy has been considered. ... Restoration of type VII collagen expression and function in dystrophic epidermolysis bullosa...
|
www.nature.com/doifinder/10.1038/nm1063
|
|
However, only a few1–4 have seriously considered the possible mechanical functions which these macromolecules, either alone or in association with non-collagen proteins, might subserve in vivo.
|
www.nature.com/nature/journal/v210/n5040/abs/2101041a0....
www.nature.com/nature/journal/v210/n5040/abs/2101041a0.html
|
|
Find a PhD is a comprehensive guide to PhD studentships and postgraduate research degrees ... We now seek to understand how integrin affinity is modulated, and whether alpha2beta1 serves a signalling as well as an adhesive function in platelets. The group also studies the interaction of non-receptor species with collagen.
|
www.findaphd.com/search/showproject.asp?projectid=256&i...
www.findaphd.com/search/showproject.asp?projectid=256&inst=camb-ubch&searchtype=i&theorder=2&page=1
|
|
Related articles in JCS ... Recent work, however, indicates that they are also important sources of biological mediators: during extracellular matrix remodelling, proteolysis of these collagens generates fragments that regulate a variety of processes, including cell proliferation, migration and apoptosis. ... In a Commentary on p.
|
jcs.biologists.org/cgi/content/full/115/22/2201/e
|
|
