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Therefore, we investigated the regulation of IL-6 expression in neurons. Membrane depolarization raised IL-6 mRNA accumulation in primary cortical cells and the PC-12 cell line. In vivo, IL-6 mRNA in the brain increased significantly after epileptic seizures.
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www.jneurosci.org/cgi/content/full/20/23/8637
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Action potential - Wikipedia, the free encyclopedia
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An action potential (or nerve impulse ) is a transient alteration of the transmembrane voltage (or membrane potential) across an excitable membrane in an excitable cell (such as a neuron or myocyt...
en.wikipedia.org/wiki/Action_potential
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This page describes how neurons work. I hope this explanation does not get too complicated, but it is important to understand how neurons do what ... This means that some event (a stimulus) causes the resting potential to move toward 0 mV. When the depolarization reaches about -55 mV a neuron will fire an action potential.
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faculty.washington.edu/chudler/ap.html
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and 2) The nonspecific (heterologous) tolerance would be associated with a partial depolarization of the tolerant cells and a decrease in the contribution of electrogenic Na(+)/K(+) pumping. ... Whole-cell patch clamp recording of neurons in brain slices demonstrated that, with electrodes containing 20 mM Na(+)
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www.medscape.com/medline/abstract/11504784
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Neurons allow the brain to communicate with the rest of the body through the propagation of waves of depolarization, known as action potentials, along the axon membrane. ... Stage 3: Depolarization ... The Structure And Function Of Neurons...
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biology.suite101.com/article.cfm/what_is_an_action_pote...
biology.suite101.com/article.cfm/what_is_an_action_potential
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The sudden complete depolarization of the membrane opens up more of the voltage-gated sodium channels in adjacent portions of the membrane. In this way, a wave of depolarization sweeps along the cell. This is the action potential (In neurons, the action potential is also called the nerve impulse.)
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users.rcn.com/jkimball.ma.ultranet/BiologyPages/E/Excit...
users.rcn.com/jkimball.ma.ultranet/BiologyPages/E/ExcitableCells.html
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Neurons displaying this depolarization block could not be activated by depolarizing current injection, but could be made to fire in response to hyperpolarization of the membrane.
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jpet.aspetjournals.org/cgi/content/abstract/238/3/1092
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Cell membranes surround neurons just as any other cell in the body has a membrane. When a neuron is not stimulated — it's just sitting with no impulse to carry or transmit — its membrane is polarized. Not paralyzed. ... This causes complete depolarization of the neuron and an action potential is created. In this state,
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www.dummies.com/how-to/content/understanding-the-transm...
www.dummies.com/how-to/content/understanding-the-transmission-of-nerve-impulses.html
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Sodium channel opens ... h gate closes ... Begin depolarization...
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www.blackwellpublishing.com/matthews/channel.html
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