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The Summer 2009 issue of “Compass” from Families of Spinal Muscular Atrophy is focused on Drug Discovery and Development programs for SMA. In particular we are highlighting the latest news on the Families of SMA Funded Therapeutic Pipeline.
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www.fsma.org/LatestNews/index.cfm?ID=4392&TYPE=1150
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Mission of the Spinal Muscular Atrophy (SMA) Foundation is to accelerate the development of a treatment or cure for Spinal Muscular Atrophy (SMA) ... The mission of the Spinal Muscular Atrophy Foundation is to accelerate the development of a treatment for SMA, the number one genetic killer of infants and toddlers.
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Spinal muscular atrophy - Wikipedia, the free encyclopedia
Spinal Muscular Atrophy ( SMA ) is a neuromuscular disease characterized by degeneration of motor neurons, resulting in progressive muscular atrophy (wasting away) and weakness. The clinical spectr...
en.wikipedia.org/wiki/Spinal_muscular_atrophy
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Spinal Muscular Atrophy (SMA) Types I, II, and III belong to a group of hereditary ... The Project is accelerating the research process by identifying drugs already in use that increase the level of SMN protein in cultured cells, which are then used as potential leads for further drug discovery and clinical testing.
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www.ninds.nih.gov/disorders/sma/sma.htm
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Distal spinal muscular atrophy (spinal CMT or HMN type II): This may clinically mimic Charcot-Marie-Tooth (CMT) disease, otherwise known as hereditary motor and sensory neuropathy (HMSN) types 1 and 2: CMT is characterized by peroneal muscular atrophy, weakness, and wasting in the legs.
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emedicine.medscape.com/article/1181436-overview
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Spinal Muscular Atrophy (SMA) refers to a group of diseases which affect the motor neurons of the spinal cord and brain stem. These critically important cells are responsible for supplying electrical and chemical messages to muscle cells. W...
http://www.fightsma.org/index.php?what_is_sma
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Spinal muscular atrophy (SMA) is an autosomal recessively inherited neuromuscular disorder with an early lethal outcome for > 50% of all patients. Today, there is no therapy for SMA available. ... Source: Expert Opinion on Drug Discovery, Volume 2, Number 4, April 2007 , pp. 437-451(15)
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www.ingentaconnect.com/content/apl/edc/2007/00000002/00...
www.ingentaconnect.com/content/apl/edc/2007/00000002/00000004/art00003
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today announced a joint collaboration to develop a promising drug candidate for the treatment of Spinal Muscular Atrophy (SMA), the leading genetically inherited cause of death of children under the age ... is engaged in the discovery and commercialization of new therapeutics that treat serious and life-threatening diseases,
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www.prnewswire.com/cgi-bin/stories.pl?ACCT=104&STORY=/w...
www.prnewswire.com/cgi-bin/stories.pl?ACCT=104&STORY=/www/story/05-17-2006/0004363673&EDATE=
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Spinal Muscular Atrophy (SMA) describes a group of diseases where motor neurons of the spinal cord and brain stem, which are critical ... Yeast Cells: Drug Discovery Factories Whitehead Institute researchers have described a new drug discovery technique which uses yeast cells to both synthesise and screen novel...
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drugdiscoveryopinion.com/2009/11/progress-in-drug-disco...
drugdiscoveryopinion.com/2009/11/progress-in-drug-discovery-for-spinal-muscular-atrophy/
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