Sensitization - Wikipedia, the free encyclopedia
Sensitization is an example of non-associative learning in which the progressive amplification of a response follows repeated administrations of a stimulus. An everyday example of this mechanism is t...
en.wikipedia.org/wiki/Sensitization
Drug addiction - Wikipedia, the free encyclopedia
Drug addiction is a pathological condition which arises due to frequent drug use. The disorder of addiction involves the progression of acute drug use to the development of drug-seeking behavior, the...
en.wikipedia.org/wiki/Drug_addiction
2. Vulnerability to Drug Addiction Current research suggests that there may be certain predisposing factors that account for individual differences in drug preference, tolerance, sensitization, abstinence signs, reinforcing efficacy, rate of acquisition of drug taking, maintenance, resistance to extinction,
www.nih.gov/grants/guide/pa-files/PA-99-033.html
The past 30 years have witnessed a substantial and growing interest in drug sensitization, particularly relating to the psychoactive and appetitive ...
www.ncbi.nlm.nih.gov/pmc/articles/PMC2099252/
Recent history has seen a surge of interest in the phenomenon of drug sensitization (reverse tolerance), in part because sensitization has been suggested as ...
www.ncbi.nlm.nih.gov/pubmed/9093812
Malignant mesothelioma may prove to be an attractive candidate for somatic gene therapy with replication-deficient recombinant adenovirus transfer of a toxic, or drug sensitization gene. ... All Medscape eMedicine Drug Reference MEDLINE...
www.medscape.com/medline/abstract/7536280
Repeated exposure to drugs of abuse induces long-lasting behavioural sensitization, which is thought to play a role in the persistence of drug-seeking behaviour. ... All Medscape eMedicine Drug Reference MEDLINE ... Prior morphine treatment resulted in long-term locomotor sensitization,
www.medscape.com/medline/abstract/10392855
Adolescent Swiss-Webster mice received intraperitoneal injections of saline, MPD (10 mg/kg) or MDMA (10 mg/kg) from PD 26 to PD 32. Animal weights were monitored during and after drug administration. One month later, cocaine-induced conditioned place preference (CPP) and locomotor activity (LMA) were investigated.
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Previous research has shown that drug sensitization, or the increase in the effect of a drug with repeated exposure, is related to relapse to drug taking in ...
research.usu.edu/undergrad/files/uploads/Newbold.URCO.S... research.usu.edu/undergrad/files/uploads/Newbold.URCO.S06.doc
Interestingly, neuroadaptation also sometimes results in an increased response to the drug (sensitization). Whether there is a diminished response or an enhanced response depends upon a variety of factors including the amount of the compound taken in and the timing of the intake.
chemcases.com/alcohol/index.htm