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Sensitization - Wikipedia, the free encyclopedia
Sensitization is an example of non-associative learning in which the progressive amplification of a response follows repeated administrations of a stimulus. An everyday example of this mechanism is t...
en.wikipedia.org/wiki/Sensitization |
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Drug addiction - Wikipedia, the free encyclopedia
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Malignant mesothelioma may prove to be an attractive candidate for somatic gene therapy with replication-deficient recombinant adenovirus transfer of a toxic, or drug sensitization gene. ... All Medscape eMedicine Drug Reference MEDLINE...
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Repeated exposure to drugs of abuse induces long-lasting behavioural sensitization, which is thought to play a role in the persistence of drug-seeking behaviour. ... All Medscape eMedicine Drug Reference MEDLINE ... Prior morphine treatment resulted in long-term locomotor sensitization,
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Adolescent Swiss-Webster mice received intraperitoneal injections of saline, MPD (10 mg/kg) or MDMA (10 mg/kg) from PD 26 to PD 32. Animal weights were monitored during and after drug administration. One month later, cocaine-induced conditioned place preference (CPP) and locomotor activity (LMA) were investigated.
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Previous research has shown that drug sensitization, or the increase in the effect of a drug with repeated exposure, is related to relapse to drug taking in ...
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Interestingly, neuroadaptation also sometimes results in an increased response to the drug (sensitization). Whether there is a diminished response or an enhanced response depends upon a variety of factors including the amount of the compound taken in and the timing of the intake.
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