The most widely accepted overall theory of aging is currently the evolutionary senescence theory of aging. ... Much experimental evidence exists to support the basic premises of the evolutionary senescence theory of aging. For example, the theory predicts that delaying the age of reproduction should delay aging,
websites.afar.org/site/PageServer?pagename=IA_b_the_evo... websites.afar.org/site/PageServer?pagename=IA_b_the_evol_senesce
Evolution of ageing - Wikipedia, the free encyclopedia
Enquiry into the evolution of ageing aims to explain why almost all living things weaken and die with age. There is not yet agreement in the scientific community on a single answer. The evolutionary...
en.wikipedia.org/wiki/Evolution_of_ageing
Any factor that decreases the rate of decline in reproductive probability intensifies selection against senescence. Any factor that increases the rate of this decline causes a relaxed selection against senescence and a greater advantage in increasing youthful vigor at the price of vigor later on.
sageke.sciencemag.org/cgi/content/abstract/2001/1/cp13
Classical evolutionary senescence theory predicts that animals from high-predation environments will experience earlier or more rapid senescence than those from low-predation environments, either as a byproduct of intense selection for increased investment in reproduction early in life or because of the accumulation...
www.plosbiology.org/article/info:doi%2F10.1371%2Fjourna... www.plosbiology.org/article/info:doi%2F10.1371%2Fjournal.pbio.0040007
The evolution of senescence may be explained by two different, but not mutually exclusive, genetic mechanisms. The antagonistic pleiotropy hypothesis predicts that senescence is a consequence of the fixation of alleles with pleiotropic effects favouring early life fitness, but bearing a cost in later life.
www.nature.com/hdy/journal/v85/n2/abs/6887370a.html
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jxb.oxfordjournals.org/cgi/reprint/erm237v1
Based on research, mainly in the animal field, two major theories of evolutionary senescence have been developed and are widely acknowledged (Kirkwood and Austad, 2000). The Antagonistic Pleiotropy Theory points out that evolution acts to maximize reproductive fitness and will allow the existence of mutations that...
jxb.oxfordjournals.org/cgi/content/full/erm237v1
LIFE TABLE TESTS OF EVOLUTIONARY THEORIES OF; SENESCENCE; RANDOLPH M. NESSE; Department of Psychiatry, C 440 Med-Inn Building, University of Michigan Medical School, Ann Arbor, Michigan 48109-0840; Abstract - The phenomenon of senescence requires both evolutionary and prox-imate explanations.
www-personal.umich.edu/~nesse/Articles/LifeTableTestsEv... www-personal.umich.edu/~nesse/Articles/LifeTableTestsEvolTheorSenes-JExpGeront-1988.PDF
To understand the evolutionary ecology of senescence, research on a broader taxonomic range is needed, incorporating field, and, where possible, longitudinal studies. ... The main focus of research on senescence is on age-related changes in mortality risk. However, evolutionary biologists focus on fitness, of which survival...
www.ingentaconnect.com/content/bsc/fecol/2008/00000022/... www.ingentaconnect.com/content/bsc/fecol/2008/00000022/00000003/art00001;jsessionid=a8j9j6nh2l1a6.alexandra?format=print
Testing evolutionary models of senescence in a natural population: age and inbreeding effects on fitness components in song sparrows.; Keller LF, Reid JM, Arcese P. Zoological Museum, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland.
www.ncbi.nlm.nih.gov/pubmed/18211879?dopt=Abstract
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