the fibrin molecules at the surface of the fibers must be stretched relative to those in the ..... Model of a fibrin molecule and protofibril. (A) Model of ...
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www.pnas.org/content/84/24/8991.full.pdf
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In an attempt to identify the region of the fibrin molecule involved in this response, we tested the effects of an antibody against a known bioactive region ...
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linkinghub.elsevier.com/retrieve/pii/S0003996903000050
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First, the spaces in the lattice may be used to host other molecules, like proteins, providing a general way to orient many copies of the particular molecule.
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www.rcsb.org/pdb/static.do?p=education_discussion/molec...
www.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/current_month.html
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New Polymerization Sites in the Bb15–53 Fragment of Fibrin Molecule ... The purpose of the study was the localization of unknown polymerization sites in central domain E of fibrin (f). There is a lot of information that except known complementary polymerization sites ‘A’-‘a’ and ‘B’-‘b’ another sites...
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www.blackwellpublishing.com/isth2005/abstract.asp?id=46...
www.blackwellpublishing.com/isth2005/abstract.asp?id=46896
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New polymerization sites in the central and peripheral domains of human fibrin molecule ... It attacks fibrinogen (F) and splits off two fibrinopeptides A. As a result F is transformed into fibrin (f) desAA, which polymerizes spontaneously by intermolecular binding of ‘A’ and ‘a’ polymerization sites giving...
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www.blackwellpublishing.com/isth2003/abstract.asp?id=77...
www.blackwellpublishing.com/isth2003/abstract.asp?id=7743
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Fibrin is a large, flexible protein composed of six proteins chains. Since it has several flexible parts, it has been difficult to study, and many of the structures in the PDB contain only part of the molecule.
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www.pdb.org/pdb/static.do?p=education_discussion/molecu...
www.pdb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb83_1.html
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Overview: Congenital dysfibrinogenemia is a term used to describe a relatively rare condition wherein an inherited abnormality in the fibrin molecule results in defective fibrin clot formation. The complications associated with abnormal clot formation range from asymptomatic ... ... In normal fibrin clot formation,
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emedicine.medscape.com/article/199723-overview
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Diagnosis: Congenital dysfibrinogenemia is a term used to describe a relatively rare condition wherein an inherited abnormality in the fibrin molecule results in defective fibrin clot formation. The complications associated with abnormal clot formation range from asymptomatic ... ... Contributor Information and Disclosures...
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emedicine.medscape.com/article/199723-diagnosis
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Indeed, EC spreading1 and proliferation2 on fibrin matrices require exposure of the ß15-42 region at the neo–N-terminus of the fibrin molecule.
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atvb.ahajournals.org/cgi/content/full/16/12/1544
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