Mechanical forces are crucial for regulating cell function. Herein, we review the effects of mechanical forces on fibroblast ECM gene expression and p...
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www.informaworld.com/smpp/content~content=a758542326~db...
www.informaworld.com/smpp/content~content=a758542326~db=all~jumptype=rss
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Reduced synthesis of collagen types I and III is characteristic of chronologically aged skin. ... The present report provides evidence that both cellular fibroblast aging and defective mechanical stimulation in the aged tissue contribute to reduced collagen synthesis.
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www.medscape.com/medline/abstract/16723701
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The Medscape Journal ... All Sources Medscape eMedicine MEDLINE Drug Reference ... In this study, the effects of relaxin in inhibiting these processes were investigated.
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www.medscape.com/medline/abstract/15956706
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Fibroblast Function In Aging: ... As expected, young fibroblasts proliferated twice as fast as aged cells. However, there was significant variability in migratory ability among aged fibroblasts, with 2 of the aged fibroblast lines demonstrating radial movement similar to that of young fibroblasts.
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www.beeson.org/researchpage.cfm?Beeson_ID=46
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Effect of FXIII on Monocyte and Fibroblast Function; Rima Dardik1, Tanya Krapp1, Esther Rosenthal2, Joseph Loscalzo3, Aida Inbal4; 1Institute of Thrombosis and Hemostasis, 2Institute of Hematology, Sheba Medical Center, Tel Hashomer and;
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content.karger.com/ProdukteDB/produkte.asp?Doi=99199
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A fibroblast is the most common type of cell found in connective tissue. Fibroblasts secrete collagen proteins that are used to maintain a structural framework for many tissues. They also play an important role in healing wounds.
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ghr.nlm.nih.gov/ghr/glossary/fibroblast
ghr.nlm.nih.gov/ghr/glossary/fibroblast
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The mutations of fibroblast growth factor receptors that give rise to dwarfism and craniosynostoses are not loss-of-function mutations. Rather, they are gain-of-function mutations that enable the FGF receptor to become active without binding its FGF ligand (Webster and Donaghue, 1996;
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8e.devbio.com/article.php?ch=14&id=151
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The findings of this study suggest that the antifibrotic effects of relaxin involve down-regulation of fibroblast activity, ... Based on this knowledge, potential antifibrotic strategies have focused on blocking naturally occurring activators of these cells or directly down-regulating their function.
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ndt.oxfordjournals.org/cgi/content/full/19/3/544
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Altered fibroblast function following myocardial infarction. ... Transforming growth factor beta1 (TGFbeta1) is a bioactive molecule that has been shown to affect fibroblast function. ... Altered fibroblast function following myocardial infarction.Altered fibroblast function following myocardial infarction.
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www.ncbi.nlm.nih.gov/pubmed/16111700
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