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I was recently diagnosed with a "tubular adenoma" of the rectum (adenomatous polyp)that was "positive for focal cytologic high grade dysplasia." Polyp APPEARS to be completely excised. Which worries me. The biopsy specimen showed an increased number of glands with glandular crowding and mucin depletion is present.
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en.allexperts.com/q/Colon-Cancer-999/2008/8/TUBULAR-ADE...
en.allexperts.com/q/Colon-Cancer-999/2008/8/TUBULAR-ADEMONA-POSITIVE-HIGH.htm
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Dysplasia - Wikipedia, the free encyclopedia
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Dysplasia (from Greek, roughly: "bad formation") is a term used in pathology to refer to an abnormality in maturation of cells within a tissue. This generally consists of an expansion of immature cel...
en.wikipedia.org/wiki/Dysplasia
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HGSIL Pap smear results mean high grade dysplasia. HGSIL is just one type of dysplasia. Though it is not cervical cancer, it can lead to cervical cancer when left untreated and unmonitored. Learn what an HGSIL Pap smear result means, how it is confirmed and treated. ... High grade squamous intraepithelial lesion,
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cervicalcancer.about.com/od/cervicaldysplasia/a/hgsil.h...
cervicalcancer.about.com/od/cervicaldysplasia/a/hgsil.htm
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High-grade dysplasia; This is considered the most advanced dysplasia with atypical changes in many of the cells and a very abnormal growth pattern of the glands. In high-grade dysplasia, the growth pattern of the glands, or rows of cells, are distorted or very irregular.
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www.barrettsinfo.com/content/3c_what_is_dysplasia.cfm
www.barrettsinfo.com/content/3c_what_is_dysplasia.cfm
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Low Grade Dysplasia and Regenerative Changes ... Focal Nodular Hyperplasia ... Colon - high grade dysplasia...
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radiology.uchc.edu/eAtlas/nav/MPGrowth.HTM
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How to manage patients with high-grade dysplasia (HGD) in Barrett's esophagus is controversial; some experts recommend esophagectomy for most patients. In 2 new studies, investigators provide additional information. ... of the remaining 66 patients, 24 had focal HGD, and 42 had diffuse HGD. During surveillance,
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general-medicine.jwatch.org/cgi/content/full/2001/703/1
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Recent reports have suggested that overexpression of the p16INK4 protein is a surrogate marker of HPV-induced high-grade dysplasia or carcinoma. However, the correlation between expression of p16INK4 and the presence of HPV DNA as determined by polymerase chain reaction (PCR) amplification has not been previously reported.
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www.medscape.com/medline/abstract/16831676?prt=true
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Sessile serrated adenomas (SSAs) show serrations typical of hyperplastic polyps but display architectural differences and lack traditional dysplasia. SSAs with foci of low- (LGD) or high-grade dysplasia (HGD) or early invasive carcinoma are seldom biopsied and, thus, are not well studied.
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www.medscape.com/medline/abstract/16938659
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We report a patient with familial adenomatous polyposis who developed high-grade dysplasia against a background of fundic gland polyposis. Two large high ... Histologically, these lesions would fall between fundic gland polyps with focal foveolar dysplasia and invasive cancer in fundic gland polyp-related carcinogenesis.
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www.nature.com/modpathol/journal/v17/n11/full/3800178a....
www.nature.com/modpathol/journal/v17/n11/full/3800178a.html
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