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jn.nutrition.org/cgi/reprint/133/3/965S
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For 17 years, LLNL researchers have been identifying these food mutagens, measuring their abundance in cooked foods typical of the Western diet, working to understand how they can trigger malignant tumors in laboratory animals that have been exposed to high mutagen doses, and estimating the importance of human exposures.
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www.llnl.gov/str/Food_Mutagens.intro.html
www.llnl.gov/str/Food_Mutagens.intro.html
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and food mutagens, bulky molecules (adducts) become ..... on food mutagens since it began 17 years ago and has led it for the past 8 years. ...
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www.llnl.gov/str/pdfs/09_95.1.pdf
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The Medscape Journal ... Allergy & Clinical Immunology ... In contrast to previous studies in rats, no carcinogen-related induction of the preneoplastic lesions aberrant crypt foci or tumors was found in the intestines of rapid and slow acetylator congenic Syrian hamsters administered PhIP or IQ.
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www.medscape.com/medline/abstract/10895988
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Krul C; Luiten-Schuite A; Baandagger R; Verhagen H; Mohn G; Feron V; Havenaar R; TNO Nutrition and Food Research Institute, Utrechtseweg 48, PO Box 360, 3700, ... IQ, MeIQ, MeIQx and PhIP) were used as model compounds for food mutagens, and the passage through TIM was investigated for each of these compounds separately.
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www.medscape.com/medline/abstract/10930699
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As part of the Laboratory's ongoing research on diet and cancer, biomedical scientist Kristen Kulp is leading a team of Livermore researchers that is combining breast cell-based assays with computational modeling and nuclear magnetic resonance (NMR) to better understand the cell-growth process. ... In the 1970s, ... (See S&TR,
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www-pls.llnl.gov/?url=science_and_technology-life_scien...
www-pls.llnl.gov/?url=science_and_technology-life_sciences-cancer_diet
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All six cooked food mutagens examined produced concentration-dependent increases in UDS in human liver slices. PhIP was the most potent compound examined, ...
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linkinghub.elsevier.com/retrieve/pii/S0278691598000064
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Competitive enzyme-linked immunosorbent assays (ELISA) with 50% inhibition by 0.4–6 pmol food mutagen were developed. The epitopes recognized by the antibodies have been characterized by ELISA using 52 synthetic analogues and metabolites of PhIP, 4,8-DiMeIQx, and other food mutagens.
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carcin.oxfordjournals.org/cgi/content/abstract/16/11/27...
carcin.oxfordjournals.org/cgi/content/abstract/16/11/2795
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By heating whatever food, hundreds of different mutagenic substances originate. The more protein food contains, the more mutagenics originate. And if we only live long enough, they cause cancer. ... The only way to effectively prevent cancer, is to prevent absorption of mutagenic substances from prepared food.
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www.13.waisays.com/cancer.htm
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