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Eventually, gene therapy will become a staple of 21st century medicine. But some experts say society will be better served if medical researchers proceed more slowly and prudently. BY JACK McCAIN; Senior Contributing Editor; ... LEADING EDGE; THE FUTURE OF GENE THERAPY;
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www.biotechnologyhealthcare.com/journal/journaldisplay....
www.biotechnologyhealthcare.com/journal/journaldisplay.cfm?aid=2/3/BH0203052.pdf
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Gene therapy has the potential to treat devastating inherited diseases for which there is little hope of finding a conventional cure. In the late 1990s, our groups in Paris, London and Milan began treating children suffering from rare immune disorders (severe combined immunodeficiencies, or SCIDs).
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www.nature.com/nature/journal/v427/n6977/full/427779a.h...
www.nature.com/nature/journal/v427/n6977/full/427779a.html
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The FDA allows gene-therapy trials for X-SCID if no other therapy is available. Clinical hold on other stem-cell gene-therapy trials may be lifted after case-by-case review. ... After a temporary hold on all trials involving retroviruses, gene-therapy trials for SCIDs and other diseases restarted in February 2003.
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www.nature.com/nature/journal/v427/n6977/box/427779a_bx...
www.nature.com/nature/journal/v427/n6977/box/427779a_bx1.html
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Dr. Tanzola: What is the American Society of Gene Therapy (ASGT) and what is its mission? ... What do you think are the implications of this work, and how do you see this technology fitting in to the future of gene therapy? ... The Future of Gene Therapy: Interview With David M. Bodine, IV, PhD...
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www.medscape.com/viewarticle/507815
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Gene therapy is the treatment of disease by replacing, altering, or supplementing a gene that is absent or abnormal and whose absence or abnormality is responsible for the disease. Gene therapy may use the genetic material, DNA, itself as the means of treatment. ... home > gene therapy - the future is here! article...
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www.medicinenet.com/script/main/art.asp?articlekey=1266...
www.medicinenet.com/script/main/art.asp?articlekey=12662
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The Future of Gene Therapy ... Gene therapy's potential to revolutionize medicine in the future is exciting, and its expectations for curing and preventing childhood diseases is encouraging. One day it may be possible to treat an unborn child for a genetic disease even before symptoms appear.
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kidshealth.org/parent/system/medical/gene_therapy.html
kidshealth.org/parent/system/medical/gene_therapy.html
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6. NIH has already provided an appropriate initial investment in gene therapy. Future gene therapy research should compete with other forms of biomedical research for funding under stringent peer review. Only with fair, yet critical, peer review will high standards be met and maintained.
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www.nih.gov/news/panelrep.html
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Gene therapy is conceptually appealing for applications in transplantation, as the donor organ is genetically manipulated ex vivo before transplantation. ... Despite encouraging results in animal models, however, clinical gene therapy trials in heart transplantation have not yet been started. The best vector and gene to...
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ejcts.ctsnetjournals.org/cgi/content/abstract/35/6/1036
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