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In contrast to tight and adherens junctions, gap junctions do not seal membranes together, nor do they restrict the passage of material between membranes. ... Gap junctions are seen with an electron microscope as patches of varying size where the plasma membranes of neighboring cells are separated by a beautifully uniform gap,
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arbl.cvmbs.colostate.edu/hbooks/cmb/cells/pmemb/junctio...
arbl.cvmbs.colostate.edu/hbooks/cmb/cells/pmemb/junctions_g.html
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Gap junctions are intercellular channels some 1.5–2 nm in diameter. These permit the free passage between the cells of ions and small molecules (up to a molecular weight of about 1000 daltons).
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users.rcn.com/jkimball.ma.ultranet/BiologyPages/J/Junct...
users.rcn.com/jkimball.ma.ultranet/BiologyPages/J/Junctions.html
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Gap junctional communication is a widespread mechanism for metabolic coupling of adjoining cells. In the immune system, evidence has built up showing that lymphocytes possess the protein building blocks of gap junctions, the connexins.
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www.jleukbio.org/cgi/content/abstract/72/4/636
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Gap Junctions Research, by the Department of Diagnostic Radiology, School of Medicine, Cardiff University, Wales, UK. ... In the vascular wall in addition to freely diffusible mediators such as nitric oxide, intercellular signalling may also involve direct communication at points of cell-cell contact via gap junctions.
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www.cardiff.ac.uk/medic/aboutus/departments/diagnosticr...
www.cardiff.ac.uk/medic/aboutus/departments/diagnosticradiology/ourresearch/endothelium/gapjunctions/index.html
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During preimplantation development several connexin proteins are expressed and assembled into gap junctions in the plasma membrane at compaction but the functional significance of connexin diversity remains controversial.
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www.reproduction-online.org/cgi/content/abstract/129/2/...
www.reproduction-online.org/cgi/content/abstract/129/2/129
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Automatic download; [Begin manual download] ... Downloading the PDF version of:; Reproduction Houghton 129 (2): 129. (128K) ... This file is in Adobe Acrobat (PDF) format. If you have not installed and configured the Adobe Acrobat Reader on your system, see Help with Printing for instructions.
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www.reproduction-online.org/cgi/reprint/129/2/129
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An imaging method termed LAMP, based on a newly described photo-activatable fluorophore, promises to illuminate how gap junctions mediate intercellular coupling.
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www.nature.com/doifinder/10.1038/nmeth0105-12
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