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The Three Dimensional Structure of the Glutathione S-Transferase of Cephalopods and its Relationship to the S-crystallin of Cephalopod Lenses.
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wwwchem.csustan.edu/chem4400/SJBR/TOBECK.htm
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Glutathione is an important tripeptide present in significant concentrations in all tissues. It contains glutamic acid, cysteine, and glycine. What is unusual about the structure of glutathione (bottom figure in the left graphic?
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www.elmhurst.edu/~chm/vchembook/564peptide.html
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lization, it was preferred not to base the choice of structure for glutathione on this compound, except to the extent of the demonstration that 2-thio- ...
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www.jbc.org/content/88/1/389.full.pdf
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On the basis of the crystal structure of the inactivated human enzyme and stopped-flow kinetic studies with two- and four-electron-reduced forms of the unreacted P. falciparum enzyme, a mechanism is proposed which explains naphthoquinone reduction at the flavin of glutathione reductase.
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www.medscape.com/medline/abstract/16910673
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The catalytic properties of four human glutathione transferases (GSTs), A1-1, M1-1, M4-4 and P1-1, were examined with 14 isothiocyanate (R-NCS) substrates. ... Structure-Activity Relationship...
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www.medscape.com/medline/abstract/7487881
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Structure, function and evolution of glutathione transferases : implications for classification of non-mammalian members of an ancient enzyme superfamily; David SHEEHAN1, Gerardene MEADE, Vivienne M. FOLEY and Catriona A. DOWD;
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www.biochemj.org/bj/360/0001/3600001.pdf
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Detailed information on Glutathione ... Glutathione is the most biologically abundant low molecular weight intracellular thiol. By way of the reducing power of its free sulfhydral (-SH), glutathione plays a key role in many cellular processes.
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www.biospecialties.com.au/about_glutathione.html
www.biospecialties.com.au/about_glutathione.html
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Antioxidative properties of NAC are well explained by the SH-group within the molecular structure which can be oxidized by certain oxygen radicals. ... Since D-NAC is not a precursor of L-cysteine, formation of glutathione cannot explain the protective effects of this isomer. L- and D-NAC may therefore act via...
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The structure of mouse liver glutathione S-transferase P1-1 complexed with its substrate glutathione (GSH) has been determined by X-ray diffraction analysis ...
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www.ncbi.nlm.nih.gov/pmc/articles/PMC1219648/
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