Protease inhibitor (pharmacology) - Wikipedia, the free encyclopedia
Protease inhibitors (PIs) are a class of medications used to treat or prevent infection by viruses, including HIV and Hepatitis C. PIs prevent viral replication by inhibiting the activity of HIV-1 pr...
en.wikipedia.org/wiki/Protease_inhibitor_(pharmacology)
The history of HIV protease inhibitors.: hiv protease inhibitors hiv protease inhibitor hoffmann la roche aids patents protease enzyme ... The History of HIV Protease Inhibitor...
inventors.about.com/library/inventors/bl_protease_inhib... inventors.about.com/library/inventors/bl_protease_inhibitors.htm
Cleavage of capsid from SP1, the final step in viral maturation, is mediated by the viral protease enzyme. Bevirimat inhibits this cleavage step by interacting with the capsid-SP1 junction in Gag, suggesting that pre-existing PI resistance mutations may have an impact on the development ... In the new study, wild-type HIV,
www.drugs.com/clinical_trials/preclinical-study-finds-p... www.drugs.com/clinical_trials/preclinical-study-finds-protease-inhibitor-resistant-hiv-may-have-reduced-potential-develop-1037.html
Images in Clinical Medicine from The New England Journal of Medicine -- Lipodystrophy Associated with an HIV-Protease Inhibitor ... Lipodystrophy Associated with an HIV-Protease Inhibito...
content.nejm.org/cgi/content/full/339/18/1296
home > hiv center > hiv a-z list > fda approves protease inhibitor for hiv infection article ... FDA Approves a Once Daily Protease Inhibitor for HIV Infection ... FDA Approves Protease Inhibitor for HIV Infection Related Articles...
www.medicinenet.com/script/main/art.asp?articlekey=2370... www.medicinenet.com/script/main/art.asp?articlekey=23703
Nelfinavir, A Lead HIV Protease Inhibitor, Is a Broad-Spectrum, Anticancer Agent that Induces Endoplasmic Reticulum Stress, Autophagy, and Apoptosis In vitro and In vivo; Clin. Cancer Res., September 1, 2007; 13(17): 5183 - 5194. [Abstract] [Full Text] [PDF];
cancerres.aacrjournals.org/cgi/content/abstract/67/3/12... cancerres.aacrjournals.org/cgi/content/abstract/67/3/1221
HIV protease inhibitors (HIV-PIs) are key components of highly active antiretroviral therapy, but they have been associated ... In our initial studies (12), we noted that the electrophoretic migration of prelamin A differed in cells treated with lopinavir and cells treated with a farnesyltransferase inhibitor (FTI).
www.jbc.org/cgi/content/full/283/15/9797
Free Online Library: Chugai to Launch HIV Protease Inhibitor INVIRASE(R) Tablet 500mg on September 15. by "JCN Newswires"; Business Pharmaceutical industry ... saquinavir /sa·quin·a·vir/ (sah-kwin´ah-vir) an HIV protease inhibitor that causes formation of immature, noninfectious viral particles; used as the base or...
www.thefreelibrary.com/Chugai+to+Launch+HIV+Protease+In... www.thefreelibrary.com/Chugai+to+Launch+HIV+Protease+Inhibitor+INVIRASE(R)+Tablet+500mg+on+...-a0151391377
TO: HIV/AIDS Health Care Providers ... Dear HIV/AIDS Health Care Provider: The purpose of this letter is to inform you of the interim results from the Adult AIDS Clinical Trials Group (ACTG) study known as A5095. ... A total of 1,147 HIV+ individuals who had never taken antiretroviral therapy enrolled in A5095.
www.nlm.nih.gov/databases/alerts/hiv.html www.nlm.nih.gov/databases/alerts/hiv.html
HIV protease inhibitor induces fatty acid and sterol biosynthesis in liver and adipose tissues due to the accumulation of activated sterol regulatory element-binding proteins in the nucleus. J. Biol. Chem. 2001. 276:37514-37519.
www.jci.org/cgi/content/full/111/3/317