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Coronavirus - Wikipedia, the free encyclopedia
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Coronaviruses were first isolated from chickens in 1937. After the discovery of Rhinoviruses in the 1950's, ~50% of colds still could not be ascribed to known agents. In 1965, Tyrrell and Bynoe used cultures of human ciliated embryonal trachea to propagate the first human coronavirus (HCoV) in vitro.
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Free Online Library: Human coronavirus NL63, France.(RESEARCH) by "Emerging Infectious Diseases"; Health, general Coronaviruses Research ... ; The human coronavirus...
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Human Coronavirus - SARS ... Bovine coronavirus ... Rat coronavirus...
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The coronaviruses can also cause both upper and, more commonly, lower respiratory tract illness in humans (group 1 [human coronavirus 229E] and group 2 [human coronavirus OC43]).
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The complete genome sequences of the human coronavirus OC43 (HCoV-OC43) laboratory strain from the American Type Culture Collection (ATCC), and a HCoV-OC43 clinical isolate, designated Paris, were obtained. Both genomes are 30,713 nucleotides long, excluding the poly(A) tail, and only differ by 6 nucleotides.
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Until recently only two human coronaviruses were known – human coronavirus (HCoV) 229E and HCoV-OC43, representatives of the group 1 and 2 coronaviruses, respectively. Both were identified in 1960s and are generally considered as common cold viruses.
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