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The brain exhibits "localization of function." This means that different parts of the brain carry out different fucntions (e.g., vision, control of voluntary movement, understanding speech, etc.) and, conversely, that not all parts of the brain do the same thing.
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facstaff.gpc.edu/~bbrown/psyc1501/brain/loclat.htm
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Understanding the mechanistic function of the Fragile X Mental Retardation Protein (FMRP) in neurons is needed to understand the molecular basis of Fragile X Syndrome, the most common inherited form of mental retardation.
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cat.inist.fr/?aModele=afficheN&cpsidt=18145283
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Localization (brain function) from Encyclopedia of Psychology provided by Find Articles at BNET ... Theories of localization first gained scientific credence in the 1860s with Paul Broca's discovery that damage to a specific part of the brain-the left frontal lobe-was associated with speech impairment.
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findarticles.com/p/articles/mi_g2699/is_0002/ai_2699000...
findarticles.com/p/articles/mi_g2699/is_0002/ai_2699000205
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Jordi Poater was born in Banyoles, Catalonia, Spain, in 1977. He received his bachelor's degree in chemistry in 1999 at the University of Girona. At the same university, in 2003 he obtained his Ph.D. in computational and theoretical chemistry, ... Miquel Duran was born in Catalonia, Spain, ... Miquel Solà was born in Fonteta,
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pubs.acs.org/doi/abs/10.1021/cr030085x
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The reaction mechanism associated with the Bergman cyclization of the (Z)-hexa-1,5-diyne-3-ene to render p-benzyne has been analyzed by means of a combined use of the electron localization function (ELF) and the catastrophe theory on the basis of density functional theory (DFT) calculations (B3LYP/6-31G(d)). ... J. Phys. Chem.
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pubs.acs.org/cgi-bin/abstract.cgi/jpcafh/2005/109/i16/a...
pubs.acs.org/cgi-bin/abstract.cgi/jpcafh/2005/109/i16/abs/jp0441947.html
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Loss-of-function mutations in that gene cause autosomal recessive distal renal tubular acidosis (Smith et al., 2000 ). The isoform 3 of the a-subunits was shown to be important for bone resorption by osteoclasts (Toyomura et al., 2000 ). ... (j) a7-GFP shows mainly cytoplasmic localization that may correspond to the ER.
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www.molbiolcell.org/cgi/content/full/17/2/917
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In this study, we present evidence to demonstrate that there is a specific lipid requirement for Rab protein localization and function. Substitution of different prenyl anchors on Rab GTPases does not lead to correct function.
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www.molbiolcell.org/cgi/content/full/14/5/1852
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The precipitating event(s) and function(s) of macrophage infiltration into WAT are unknown. ... These results provide a novel framework for understanding macrophage recruitment, function, and persistence in WAT of obese individuals.
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www.jlr.org/cgi/content/abstract/46/11/2347
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These results provide a novel framework for understanding macrophage recruitment, function, and persistence in WAT of obese individuals. ... Results are presented as means ± SD. ... We next investigated the relationship between WAT macrophage localization and obesity-associated adipocyte death in human subjects.
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www.jlr.org/cgi/content/full/46/11/2347
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