DNA mismatch repair - Wikipedia, the free encyclopedia
DNA mismatch repair is a system for recognizing and repairing erroneous insertion, deletion and mis-incorporation of bases that can arise during DNA replication and recombination, as well as repairin...
en.wikipedia.org/wiki/DNA_mismatch_repair
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DNA repair - Wikipedia, the free encyclopedia
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DNA repair refers to a collection of processes by which a cell identifies and corrects damage to the DNA molecules that encode its genome. In human cells, both normal metabolic activities and environ...
en.wikipedia.org/wiki/DNA_repair
Base Excision Repair (BER) ... Mismatch Repair (MMR) ... Mismatch repair deals with correcting mismatches of the normal bases; that is, failures to maintain normal Watson-Crick base pairing (A•T, C•G)
users.rcn.com/jkimball.ma.ultranet/BiologyPages/D/DNAre... users.rcn.com/jkimball.ma.ultranet/BiologyPages/D/DNArepair.html
Mismatch repair (MMR)--Correction of mismatched nucleotides and small loops ... Genes Encoding Enzymes of Mismatch Repair ... The mechanism of mismatch repair was first thoroughly studied in E. coli. The research groups of Modrich, Kolodner and others re-constituted the repair process from purified proteins.
asajj.roswellpark.org/huberman/dna_repair/mmr.html asajj.roswellpark.org/huberman/dna_repair/mmr.html
There are three major DNA repairing mechanisms: base excision, nucleotide excision and mismatch repair. ... Mismatch repair in eukaryotes may be similar to that in E. coli. Homologs of MutS and MutL have been identified in yeast, mammals, and other eukaryotes. MSH1 to MSH5 are homologous to MutS; MLH1, PMS1 and PMS2...
www.web-books.com/MoBio/Free/Ch7G.htm
The European Bioinformatics Institute ... The mismatch repair system promotes genomic fidelity by repairing base-base mismatches, insertion-deletion loops and heterologies generated during DNA replication and recombination...
www.ebi.ac.uk/ego/DisplayGoTerm?id=GO:0006298
InterPro: IPR002099 DNA mismatch repair protein ... IPR014763 DNA mismatch repair protein, N-terminal 2 - 337 ... IPR002099 DNA mismatch repair protein 65 - 873...
www.ebi.ac.uk/interpro/IEntry?ac=IPR002099
2. Mismatch repair ... Human mismatch repair proteins have recently been identified and are very similar to those of the prokaryote E. coli and the simple eukaryote yeast (this is an old invention of cells); mutations are found to be passed in the germline of families with some types of inherited colon cancer (HPNCC).
www-personal.ksu.edu/~bethmont/mutdes.html
Here, we review some data suggesting that the inactivation of mismatch repair is often found in endometrial cancer and we discuss molecular-based strategies that would help to identify the affected individuals in families with cases of glandular malignancies.
www.ebmonline.org/cgi/content/full/227/8/579
DNA mismatch repair (MMR) is an evolutionarily conserved process that corrects mismatches generated during DNA replication and escape proofreading.
www.ncbi.nlm.nih.gov/pubmed/15952900
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