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Multiple drug resistance - Wikipedia, the free encyclopedia
Multiple drug resistance or Multidrug resistance is a condition enabling a disease-causing organism to resist distinct drugs or chemicals of a wide variety of structure and function targeted at era...
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Multi-drug-resistant tuberculosis - Wikipedia, the free encyclopedia
Multi-drug resistant tuberculosis ( MDR-TB ) is defined as TB that is resistant at least to isoniazid (INH) and rifampicin (RMP), the two most powerful first-line anti-TB drugs. Isolates that are m...
en.wikipedia.org/wiki/Multi-drug-resistant_tuberculosis |
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Drug resistance arises due to the improper use of antibiotics in chemotherapy of drug-susceptible TB patients. This improper use is a result of a number of actions, including administration of improper treatment regimens by health-care workers and failure to ensure that patients complete the whole course of treatment.
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This resistance results from the use of antimicrobials both in humans and animal husbandry. Multi-drug resistance to "critically important antimicrobials"2 are compounding the problems.
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The intestinal efflux pump P-glycoprotein (P-gp), the product of the multi-drug resistance-1 (MDR-1) gene, significantly influences the pharmacokinetics of several drugs. ... The intestinal efflux pump P-glycoprotein (P-gp), the product of the multi-drug resistance-1 (MDR-1) gene, significantly influences the...
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OBJECTIVE: To study the relationship between soluble resistance-related calcium-binding protein (sorcin) gene and multidrug resistance gene (mdr1), and their significance in clinical drug resistance and prognosis of acute myeloid leukemia (AML). ... Drug Resistance, Multiple...
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