Anaphylaxis
Anaphylaxis is a life-threatening type of allergic reaction... More »
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Anaphylaxis - Wikipedia, the free encyclopedia
Anaphylaxis is an acute systemic (multi-system) and severe type I hypersensitivity allergic reaction in humans and other mammals. The term comes from the Greek words ανα ana (against) and φύλαξις ...
en.wikipedia.org/wiki/Anaphylaxis
Upon reexposure to the sensitized allergen, the allergen may cross-link the mast cell or basophil surface-bound allergen-specific IgE resulting in cellular degranulation as well as de novo synthesis of mediators.[7] Histamine is thought to be the primary mediator of anaphylactic shock.
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A century has passed since the discovery of anaphylaxis, and much knowledge has been added to our understanding of this syndrome. This article reviews the pathophysiology, recognition, and treatment of anaphylactic shock.
www.medscape.com/viewarticle/497498
The pathophysiology of anaphylactic shock is that when the antibody-antigen response is triggered they in turn trigger the release of biochemical mediators. These mediators have a two-fold effect. First vasoconstriction of the airways occurs making it hard to breath.
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The balance of evidence from human observations and animal studies suggests that the main pathophysiologic features of anaphylactic shock are a profound ...
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Your browser version may not work well with NCBI's Web applications. More information here... ... Anaphylactic shock: pathophysiology, recognition, and treatment. ... [Treatment of anaphylactic shock]
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Mitsuhata, H, Shimizu, R, Yokoyama, MM. Role of nitric oxide in anaphylactic shock. J Clin Immunol 1995; 15:277. ... Brown, SG. The pathophysiology of shock in anaphylaxis. Immunol Allergy Clin North Am 2007; 27:165.
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BioInfoBank Library :: Anaphylactic shock: pathophysiology, recognition, and treatment. Cardiac anaphylaxis: pathophysiology and therapeutic perspectives. Carboplatin hypersensitivity reactions. Chemotherapy and biotherapy-induced hypersensitivity reactions. ... [Modern treatment concepts of anaphylactic reactions]
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Hypovolemia rapidly ensues during anaphylactic shock with up to 40 percent loss of intravascular fluid into the interstitial space during reactions, as demonstrated by hemoconcentration. Therefore, volume expansion is extremely important in conjunction with epinephrine ... Levy JH, Fisher MMc: Pathophysiology of anaphylaxis.
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