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Physical dependence - Wikipedia, the free encyclopedia
Physical dependence refers to a state resulting from chronic use of a drug that has produced tolerance and where negative physical symptoms of withdrawal result from abrupt discontinuation or dosage ...
en.wikipedia.org/wiki/Physical_dependence |
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Addiction - Wikipedia, the free encyclopedia
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The clinical presentation of substance use disorders often includes the element of physiological dependence, defined as "a state of adaptation to a drug or alcohol, usually characterized by the development of tolerance to drug effects and the emergence of a withdrawal syndrome during prolonged abstinence" (Rinaldi et...
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Differing views of its potential for producing dependence are discussed. The consensus opinion is taken to be that a risk of psychological dependence does exist, but only one case has appeared in the medical literature to date of physiological dependence on chlormethiazole, with withdrawal symptoms.
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Physiological dependence -- A state of dependency or addiction in which one has physically adapted to a substance and often requires increasing amounts to achieve the same effect. Physical distress may be experienced upon discontinuing use of the drug.
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A multidimensional assessment battery able to diagnose the presence of physiological dependence according to each of three systems--the criteria of DSM-IV alternative dichotomous criteria and a dimensional scale--was administered about 2 weeks after admission, and 241 subjects were reinterviewed 6 months later.
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Addiction and Dependence; (See: Drugs in American Society, 5th, 6th, and 7th editions, Erich Goode, McGraw-Hill, 1999/2007. Chapter 1. ... Psychological and Physiological Dependence are separate, independent and overlapping phenomena ... Psychological dependence exists along a continuum. Physiological dependence is either/or.
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