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Excitation-contraction coupling (ECC) is the process whereby an action potential triggers a myocyte to contract. When a myocyte is depolarized by an action potential, calcium ions enter the cell during phase 2 of the action potential through L-type calcium channels located on the sarcolemma.
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www.cvphysiology.com/Cardiac%20Function/CF022.htm
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(b) The inactivation process of Na+ current was significantly delayed with no change of its amplitude; (c) The overall intracellular Na+ and Ca2+ concentration could be augmented in the presence of BmK I; (p <0.05);
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www.medscape.com/medline/abstract/15649631
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We have tested the hypothesis that caveolae modulate excitation-contraction coupling (ECC) and beta-adrenergic stimulation in the adult cardiac myocyte. METHODS: Shortening, [Ca(2+)](i) and L-type Ca(2+) current (I(Ca,L)) were recorded in rat ventricular myocytes.
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www.medscape.com/medline/abstract/16318846
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process of converting an electrical stimulus to mechanical response [1] . This process is fundamental to muscle physiology, whereby the electrical stimulus is usually an action potential and the mechanical response is contraction. EC coupli...
http://wiki.answers.com/Q/Describe_the_Process_of_excit...
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Excitation Contraction Coupling I. Turning the idea of movement into muscle contractions A. The train of physiological events that run from the moment the brain decides to initiate a muscle contraction to the actual contraction are termed Excitation Contraction Coupling (EC Coupling).
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www.holycross.edu/departments/biology/kprestwi/exphys/l...
www.holycross.edu/departments/biology/kprestwi/exphys/lecture/ExPhysEx1Lect_pdf/ExPhys_03_L06_ECC.pdf
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The T-tubules are essential structures for excitation-contraction coupling. T-tubules are tube-shaped invaginations of the sarcolemma (skeletal muscle plasma membrane) that penetrate throughout the muscle fiber (red in Figure 16-73A).
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courses.washington.edu/conj/bess/muscle/eccoupling.html
courses.washington.edu/conj/bess/muscle/eccoupling.html
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It is crucial to the very process that enables the chambers of the heart to contract and relax, a process called excitation-contraction coupling.
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www.ncbi.nlm.nih.gov/pubmed/11805843
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Conclusions: Caveolae modulate ECC via the efficiency of the Ca2+-induced Ca2+ release process, rather than Ca2+ influx. Our data are also consistent with the hypothesis that interaction of Gi protein cascade components with caveolin in the caveolae is necessary for effective signalling by this pathway.
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cardiovascres.oxfordjournals.org/cgi/content/abstract/6...
cardiovascres.oxfordjournals.org/cgi/content/abstract/69/4/816
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remodeling of this process of excitation-contraction cou- pling (ECC) may be of fundamental ..... Bers DM: Cardiac excitation-contraction coupling. Nature ...
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www.springerlink.com/index/G22W860613T81247.pdf
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