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Carcinoid tumors often have no symptoms, however, they may cause carcnoid syndrome. ... The damage to the tricuspid and pulmonic valves of the heart in the carcinoid syndrome is most likely caused by prolonged exposure to high levels of serotonin in the blood.
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www.medicinenet.com/carcinoid_syndrome/article.htm
www.medicinenet.com/carcinoid_syndrome/article.htm
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The name was chosen to separate these tumors from ordinary malignancies, but by the 1950s, the fact that carcinoids could be malignant was obvious, thanks to Erspamer and Asero (1952), who identified serotonin production by carcinoid tumors.6 This finding, built on research conducted in the first half of the 20th...
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emedicine.medscape.com/article/282515-overview
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Excess serotonin levels cause carcinoid syndrome. ... Hydroxytryptamine (serotonin) secreted by the carcinoid tumor is degraded in the liver to 5-HIAA and excreted in urine. Significantly higher levels of 5-HIAA are found in carcinoid syndrome. Calculations are performed by using a 24-hour collection of urine.
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emedicine.medscape.com/article/364581-overview
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The blood returning to the left side of the heart has normal levels of serotonin. Carcinoid Heart Disease is a result of thickening of the pulmonic and tricuspid heart valves, as a result of prolonged exposure to high levels.
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www.carcinoid.org/pcf/lectures/docs/BiochemMarkers.htm
www.carcinoid.org/pcf/lectures/docs/BiochemMarkers.htm
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Background Although serotonin has been postulated as an etiologic agent in the development of carcinoid heart disease, no direct evidence for different ambient serotonin levels in cardiac and noncardiac patients has been reported to date.
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www.circ.ahajournals.org/cgi/content/abstract/92/4/790
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Although serotonin has been indirectly linked to carcinoid heart disease, no direct evidence for different ambient serotonin levels in carcinoid cardiac and noncardiac patients has previously been reported.
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www.circ.ahajournals.org/cgi/content/full/92/4/790
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Sandostatin (octreotide) injections are sometimes given to people with advanced carcinoid tumors that cannot be removed with surgery. ... Some common medicines, like selective serotonin reuptake inhibitors (SSRIs, such as Paxil, Serzone, and Prozac) may make symptoms worse by increasing levels of serotonin. However,
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www.nlm.nih.gov/medlineplus/ency/article/000347.htm
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Symptoms of Carcinoid syndrome including signs, symptoms, incubation period, duration, and correct diagnosis. ... General information about symptoms of Carcinoid syndrome: The symptom information on this page attempts to provide a list of some possible symptoms of Carcinoid syndrome. ... Serotonin inhibits insulin production...
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www.cureresearch.com/c/carcinoid_syndrome/symptoms.htm
www.cureresearch.com/c/carcinoid_syndrome/symptoms.htm
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This test may be done to diagnose carcinoid syndrome. Many patients with carcinoid syndrome will have high levels of serotonin in blood and urine.
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www.nlm.nih.gov/medlineplus/ency/article/003562.htm
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