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Alternate Name(s): Stromal tumor; Gonadal stromal tumor; Sex cord tumor; Androblastoma ... The outcome of this disease depends on the extent of disease and the ability to completely remove the tumor with surgery. The overall 5-year survival rate is around 70-90%. Fortunately, arrhenoblastoma has a low chance of spreading (metastasis). ...
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www.nlm.nih.gov/medlineplus/ency/article/001507.htm#Exp...
www.nlm.nih.gov/medlineplus/ency/article/001507.htm#Expectations%20(prognosis)
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Familial gastrointestinal stromal tumor (GIST) is a rare autosomal dominant genetic disorder. We report the second family to date with a germline point mutation in exon 17 of the KIT gene that leads to substitution of aspartic acid at position 820 with tyrosine (D820Y).
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www.thedoctorsdoctor.com/diseases/stromal_tumors_gi.htm
www.thedoctorsdoctor.com/diseases/stromal_tumors_gi.htm
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Key Words: chemotherapy, gastrointestinal stromal tumor, imatinib mesylate (Gleevec™). (Definitions of many terms related to cancer can be found in the Cancer.gov Dictionary.) ... Prognosis tends to be poor, even for early tumors that can be removed by surgery. Treatment with traditional chemotherapy and radiation...
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www.cancer.gov/clinicaltrials/results/gleevec-shows-pro...
www.cancer.gov/clinicaltrials/results/gleevec-shows-promise0202
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Gastrointestinal stromal tumors (GISTs) are fairly rare tumors of the GI tract. In the past, they were thought to start in muscle or nerve cells in the GI tract. This is because the tumor cells look like muscle or nerve cells under the microscope.
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www.cancer.org/docroot/cri/content/cri_2_4_1x_what_are_...
www.cancer.org/docroot/cri/content/cri_2_4_1x_what_are_gastrointestinal_stromal_tumors.asp
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It is also often helpful in predicting the patient's prognosis (the course of the disease and outlook) .To help stage the tumor, doctors may use several types of imaging, endoscopy, or other tests, such as those described in the previous section ("How are gastrointestinal stromal tumors diagnosed?").
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www.cancer.org/docroot/CRI/content/CRI_2_4_3x_How_Are_G...
www.cancer.org/docroot/CRI/content/CRI_2_4_3x_How_Are_Gastrointestinal_Stromal_Tumors_Staged.asp
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OBJECTIVE: To evaluate the clinical signification of c-kit gene mutation in gastrointestinal stromal tumor (GIST) and examine whether the presence of mutation of c-kit gene is important as a prognostic factor.
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www.medscape.com/medline/abstract/15062057
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Other factors with poor prognosis include tumor rupture, distal location, high cellularity, tumor necrosis, the presence of metastases or invasion, and mutation in the c-kit gene.1, 2, 6, 10 Findings from 2 studies show that with microscopic resection, margins are not ... Media file 2: Gastrointestinal stromal tumor.
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www.emedicine.com/radio/topic388.htm
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