Contents of this page: Actin structure & polymerization; Capping & crosslinking proteins; Cell structures that involve actin; Nucleation of actin filament formation; ... Usually profilin promotes actin polymerization. It may function as a carrier, donating the actin monomer to the plus end of a filament.
www.rpi.edu/dept/bcbp/molbiochem/MBWeb/mb2/part1/actin.... www.rpi.edu/dept/bcbp/molbiochem/MBWeb/mb2/part1/actin.htm
Actin - Wikipedia, the free encyclopedia
Actin is a globular, roughly 42-kDa protein found in all eukaryotic cells (the only known exception being nematode sperm) where it may be present at concentrations of over 100 μM. It is also one of t...
en.wikipedia.org/wiki/Actin
The discrepancies between the two models underscore that the definite structure of the F-actin filament at atomic scale has remained elusive. In particular, there are considerable uncertainties regarding the highly mobile N-terminus, but also the C-terminal helix ... Modulating F-actin filament assemby and structure...
www.scripps.edu/~stoffler/publ/PDF/MRT99/MRTReview99.ht... www.scripps.edu/~stoffler/publ/PDF/MRT99/MRTReview99.html
Oct 26, 2007 ... What are the functions of these different modes within F-actin? ..... Top; An Actin-like Superfamily; The Structure of the Filament ...
www.jbc.org/content/282/50/36133.full
Together, these results extend our understanding of how CP binds to the barbed end of the actin filament, and they support the idea that CP can “wobble” when bound to the barbed end solely by the C-terminal “tentacle” of its beta subunit.
www.jbc.org/cgi/content/abstract/M609850200v1
ACTIN STRUCTURE AND FUNCTION. 51 structural information is available at the ..... Structure of the Actin Filament. The actin filament can be described as a ...
arjournals.annualreviews.org/doi/pdf/10.1146/annurev.bb... arjournals.annualreviews.org/doi/pdf/10.1146/annurev.bb.21.060192.000405
Structure / function analysis of the interaction of PIP2 with actin capping protein: Implications for how capping protein binds the actin filament.
www.cooperlab.wustl.edu/Data/PIP2_KKT/PIP2_KKT.html
The purpose of this study was to address whether Tm isoforms are able to spatially specify actin filament function. One mechanism by which Tms may function is by recruiting and/or regulating the activities of other actin-binding proteins.
www.molbiolcell.org/cgi/content/full/14/3/1002
The Function of Plakophilin 1 in Desmosome Assembly and Actin Filament Organizatio ... To address the function of plakophilin 1 in desmosome assembly and structure, we studied targeting of its domains in epithelial cells and analyzed its direct binding partners in the yeast two-hybrid system. Fig. 1 a summarizes the...
jcb.rupress.org/cgi/content/full/149/1/209
When used in combination with DPNTP, latrunculin A, which disassembles actin filaments and disrupts adherens junctions, led to dissociation up to an order of magnitude greater than either treatment alone.
jcb.rupress.org/cgi/content/full/159/6/1005