This image represents the structure of an antibody's variable region (Fab) complexed with an antigen, in this case hen egg white lysozyme. The other images in this section are derived from this structure.
www.biology.arizona.edu/immunology/tutorials/antibody/s... www.biology.arizona.edu/immunology/tutorials/antibody/structure.html
These particular residues seem to be located centrally in the binding site as indicated by a structure model analysis. The importance of several of these conserved residues was supported by their presence in a mouse monoclonal antibody with a known structure and the same epitope specificity.
www.medscape.com/medline/abstract/11287680
The location and description of epitopes on proteins describe the basis of immunological specificity. ... The 2.8-A structure of the phosphocarrier protein, HPr from Escherichia coli, complexed to the Fab fragment of the monoclonal antibody, Jel42, has been determined.
www.medscape.com/medline/abstract/7684366
Antibody - Wikipedia, the free encyclopedia
Antibodies (also known as immunoglobulins , abbreviated Ig ) are gamma globulin proteins that are found in blood or other bodily fluids of vertebrates, and are used by the immune system to identi...
en.wikipedia.org/wiki/Antibody
Structure of an Antibody; It is important to learn about the structure of an antibody and why they are such important molecules in immunocytochemistry ... What Is It? ... Antibody Staining?
www.wellesley.edu/Biology/Concepts/Html/antibody.html www.wellesley.edu/Biology/Concepts/Html/antibody.html
Antibody Development ... Antibody Overview ... Antibody Evolution...
www.medarex.com/Development/Structure.htm www.medarex.com/Development/Structure.htm
Brief Introduction to Antibody Structure ... The basic structure of all antibody or immunoglobulin (Ig) molecules consists of 4 protein chains shaped like a capital letter "Y" and linked by disulphide bonds. There are two pairs of chains in the molecule: heavy and light.
www.cryst.bbk.ac.uk/~ubcg07s/Intro.html
Visit the page of information and links to accompany my book chapter Protein Sequence and Structure Analysis of Antibody Variable Domains. In: Antibody Engineering Lab Manual (Ed.: Duebel, S. and Kontermann, R., Springer-Verlag, Heidelberg).
www.bioinf.org.uk/abs/
The structure of the combining site of the DNP binding IgA mouse myeloma protein MOPC 315 has been determined by a combination of high resolution nuclear magnetic resonance, electron spin resonance, model building and chemical modifications.
www.nature.com/nature/journal/v266/n5597/abs/266031a0.h... www.nature.com/nature/journal/v266/n5597/abs/266031a0.html
Abcam - Antibodies & Reagents, find any antibody. ... An antibody is defined as an immunoglobulin (glycoprotein) capable of specific combination with the antigen that caused its production in a susceptible animal. They are produced in response to the ... Resources > Abcam's antibody guide > Antibody structure and isotypes...
www.abcam.com/index.html?pageconfig=resource&rid=11258&... www.abcam.com/index.html?pageconfig=resource&rid=11258&pid=11287