When you apply two drugs to a system, you can get either the same response as the sum of the two drugs individually (additive), a greater response (synergistic) or a smaller response (if one drug blocks the effects of the other).
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Synergy - Wikipedia, the free encyclopedia
Synergy (from the Greek , meaning working together) is the term used to describe a situation where different entities cooperate advantageously for a final outcome. Simply defined, it means that the w...
en.wikipedia.org/wiki/Synergy
The objective of the present work was to enhance the activity of these drugs by their combination with other drugs active against T. gondii. METHODS: Mice infected ip with 250 LD100 of strain RH tachyzoites ... Combination of sub-curative doses of A with P, S or D were highly synergistic and induced significant protection.
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Another object of the invention is to provide local delivery of two or more synergistic pharmacologic agents or delivery of two or more non-synergistic pharmacologic agents. ... The totally erodible drug delivery device is capable of delivering two or more synergistic drugs over a prolonged period.
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Antibacterial compositions comprising (1) a rifamycin derivative represented by the formula (I) or its physiologically acceptable salt, and (2) a proton pump inhibitor (a) or a bismuth preparation (b) wherein the components (1) and (2) are used in such amounts as producing a synergistic effect against Helicobacter pylori,
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In one embodiment, the pharmaceutical compounds of the present invention are delivered in a totally erodible drug delivery device capable of delivering two or more synergistic drugs over a prolonged period.
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Our goals were to study the sequence specific and synergistic binding of three drugs having distinctly different binding modes: actinomycin D (ACTD), an intercalator with GpC sequence preference; chromomycin A3 (CHR), a guanine specific minor groove binder; ... and distamycin A (DST), ... Medicine Medicine and Medical Research...
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Proposal was made to study the sequence specific binding and synergistic effect of three drugs having distinctly different binding modes: actinomycin D (ACTD), a guanine specific intercalator; chromomycin A3 (CHR), a guanine specific minor groove binder; ... To investigate the possible synergistic effects of drugs on DNA binding,
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Researchers in the Tumor Immunobiology Program of the James Graham Brown Cancer Center, University of Louisville, Kentucky, studied the synergistic effects of Imprime PGG in combination with Avastin in a xenograft mouse model where human ovarian cancer cells were implanted into the mice. ... Alcohol / Addiction / Illegal Drugs...
www.medicalnewstoday.com/articles/99229.php
See how reseachers are using Origin's LabTalk scripting language to perform research! Data analysis is easy with Origin! ... Yet, no one has ever looked for synergistic effects between ATG and CyA, despite the wide use of both drugs, partly because of the difficulty of distinguishing between the effects of two such...
www.originlab.com/index.aspx?s=9&lm=68&pid=215
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