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Anhydrotetrodotoxin 4-epitetrodotoxin, or Tetrodotoxin, as it is more easily referred to, is 10,000 times more lethal than cyanide. It is perhaps the most potent toxin present in nature, save two others, which occur in bacteria.
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puffernet.tripod.com/tetrodotoxin.html
puffernet.tripod.com/tetrodotoxin.html
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Tetrodotoxin - Wikipedia, the free encyclopedia
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Tetrodotoxin (also known as "tetrodox" and frequently abbreviated as TTX ) is a potent neurotoxin with no known antidote. There have been succesful tests of a possible antidote in mice, but further...
en.wikipedia.org/wiki/Tetrodotoxin
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The toxic dose is not clear because puffer fish have different concentrations of tetrodotoxin. A dose of 1-2 mg of purified toxin can be lethal. Reported cases from the Centers for Disease Control and Prevention (CDC) have documented toxicity with ingestion of as little as 1.4 ounces of puffer fish.
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emedicine.medscape.com/article/818763-overview
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Tetraodontidae - Wikipedia, the free encyclopedia
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Tetraodontidae is a family of primarily marine and estuarine fish. The family includes many familiar species which are variously called puffers , balloonfish , blowfish , bubblefish , globef...
en.wikipedia.org/wiki/Tetraodontidae
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Tetrodotoxin (TTX, CAS Number [4368-28-9]) is a potent marine neurotoxin, named after the order of fish from which it is most commonly associated, the Tetraodontiformes (tetras-four and odontos-tooth), or the tetraodon pufferfish.
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www.chm.bris.ac.uk/motm/ttx/ttx.htm
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Provides basic facts about tetrodotoxin. ... Tetrodotoxin (anhydrotetrodotoxin 4-epitetrodotoxin, tetrodonic acid) ... The gonads, liver, intestines, and skin of pufferfish can contain levels of tetrodotoxin sufficient to produce rapid and violent death. The flesh of many pufferfish may not usually be dangerously toxic.
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vm.cfsan.fda.gov/~mow/chap39.html
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; Home Units Defensive Mechanisms Tetrodotoxin: Mode of Action ... Tetrodotoxin is the poison that is produced by the puffer fish and a number of other animals. It is a virulent poison, the LD50 for the mouse is 10 nanograms. It acts by blocking the conduction of nerve impulses along nerve fibers and axons.
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www.life.umd.edu/grad/MLfsc/zctsim/ionchannel.html
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None available. Sensitive chemical assays for tetrodotoxin have been developed but not approved for use. ... Tetrodotoxin binds to the sodium channel of the nerve preventing the passage of sodium ions through the cell membrane and therefore of the nerve impulse. Although its target is very similar to that of saxitoxin,
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www.cbwinfo.com/Biological/Toxins/TTX.html
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[tĕ-trṓdə-tŏḱsĭn]
