Therapeutic index - Wikipedia, the free encyclopedia
The therapeutic index (also known as therapeutic ratio ), is a comparison of the amount of a therapeutic agent that causes the therapeutic effect to the amount that causes death. Quantitatively, i...
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The ratio of the drug dose which produces an undesired effect to the dose which causes the desired effects is a therapeutic index and indicates the selectivity of the drug and consequently its usability.
web.vet.cornell.edu/public/pharmacokinetics/sitesDA/the... web.vet.cornell.edu/public/pharmacokinetics/sitesDA/therapeutic_index.html
PURPOSE: New strategies that target selected molecular characteristics and result in an effective therapeutic index are needed for metastatic, hormone-refractory prostate cancer. ... For tumor to marrow therapeutic index improvement in future studies, anti-MUC1 scFvs modules were developed for pretargeted radioimmunotherapy.
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Definition of therapeutic index in the Medical Dictionary. therapeutic index explanation. Information about therapeutic index in Free online English dictionary. What is therapeutic index? Meaning of therapeutic index medical term. ... therapeutic index  originally, the ratio of the maximum tolerated dose to the...
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The Therapeutic Index of a drug is the ratio of the toxic to the therapeutic dose. Drugs with a low therapeutic index may only require a small increase in dose to produce toxic effects.
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The therapeutic index is often used to rank the net effectiveness of drugs and to provide a guide for choosing the best among several drugs.
www.sciencemag.org/cgi/content/abstract/144/3623/1212
Britannica online encyclopedia article on therapeutic index (pharmacology), ...the dose needed for the desired effect and the dose that produces unwanted and possibly dangerous side effects. This relationship, termed the therapeutic index, is defined as the ratio LD50:ED50. ... This relationship, termed the therapeutic index,
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