In response to water loading or diuresis, cells of the renal medulla encounter a markedly hypotonic milieu (20). In addition, the total solute concentration of a markedly hypertonic renal medullary interstitium, achievable in the face of avid water conservation and comprising a total solute burden >2,000 mosM,
ajpcell.physiology.org/cgi/content/full/275/4/C1104
Mean blood pressure rose significantly in both groups and hypertensive subjects exhibited a greater rise of systolic blood pressure (16 mm Hg) than normotensive subjects (8 mm Hg) 20 minutes after water loading. The maximum diuresis and natriuresis corresponded to the period in which the rise of blood pressure was greatest.
hyper.ahajournals.org/cgi/content/short/9/4/407
Water loading was used as a diagnostic test in the study of renal excretion of water and sodium during the clinical stages of cirrhosis of the liver in 25 patients free from clinical and instrumental signs of ascites, 26 with treatable ascites, and 14 with intractable ascites.
lib.bioinfo.pl/pmid:6856172
Excretion of proteins increased from 132 +/- 78 to 365 +/- 80 microg at water loading (p < .01) and to 423 +/- 143 microg after injection 1-desamino-8-arginine vasotocin (p < .01). Direct dependence was revealed between increase of diuresis and renal protein excretion.
lib.bioinfo.pl/pmid:3133226
PGE2 has an established role in renal water handling. The present study was undertaken to examine the role of microsomal prostaglandin E synthase-1 (mPGES-1) in the diuretic response to acute and chronic water loading. ... water loading; aquaporin-2; collecting duct; diuresis...
ajprenal.physiology.org/cgi/content/abstract/296/5/F112... ajprenal.physiology.org/cgi/content/abstract/296/5/F1129
To investigate the ability to retain fluid in the body, normohydrated camels were loaded with water or isotonic saline (0.1 l/kg body wt) by esophageal tube. After water loading plasma osmolality decreased and a water diuresis was seen, but it took 3 days until the body weight returned to prehydration level.
ajpregu.physiology.org/cgi/content/short/262/5/R915
The renal effects of the nitric oxide (NO) synthase inhibitor nitro-L-arginine methyl ester (L-NAME) were investigated in conscious dogs undergoing sustained water diuresis and replacement of urinary sodium losses. ... Renal nerves and nNOS: roles in natriuresis of acute isovolumetric sodium loading in conscious rats;
ajpregu.physiology.org/cgi/content/abstract/281/2/R584
Water deprivation prior to water loading reduced the excretion of water by DI animals far below that of normal rats regardless of the route of administration. Salt loading, on the contrary, obviated the influence of prior water deprivation and in ... Pitressin failed to produce an antidiuretic effect during saline diuresis;
ajplegacy.physiology.org/cgi/content/abstract/197/1/173
During 2h acute water loading, the diuresis was accompanied by an elevation in renomedullary HA (+45%) while cortical HA was unaffected. In both the L-NAME and indomethacin-treated animals, the water loading-induced elevation in renomedullary HA was absent indicating a crucial involvement of NO and prostaglandins.
www.blackwellpublishing.com/aphmeeting/abstract.asp?Mee... www.blackwellpublishing.com/aphmeeting/abstract.asp?MeetingID=&id=61401
Bull Mem Soc Med Hop Paris. 1967; 118(2):123-7 (ISSN: 0366-1334) ... Water [diagnostic use] ... 7732-18-5 (Water)
www.medscape.com/medline/abstract/6061575
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