A look at genetic mutations and how and why they occur. ... If this non-disjunction occurs in chromosome 21 of a human egg cell, a condition called Down's syndrome occurs. This is because their cells possess 47 chromosomes as opposed to the normal chromosome compliment in humans of 46.
www.biology-online.org/2/7_mutations.htm
Monosomy is prresence/absence of one of the chromosome of a pair. eg. for sex chromosomes normal condition is XX or XY some times due to non disjunction the individual become XO. here O means no chromosome. this is called Turner's syndrome.
www.biology-online.org/dictionary/Disjunction www.biology-online.org/dictionary/Disjunction
In an abstract (Records Genetics Society-1944, p. 14) it was reported that chromosome disjunction in a plant heterozygous for interchange T5-6c was markedly changed when the position of the chromosome 5 centromere was shifted nearer the center of the cross by the presence of a homozygous inversion in chromosome 5.
www.agron.missouri.edu/mnl/19/23Burnham.htm
Chromosome disjunction (See News Letter 19:31. 1945). ... When the inversion is in the translocated chromosome, crossovers within the inversion do not give rise to the cytologically recognizable half-disjunction" quartets; whereas when the inversion is in the normal chromosome these crossovers are recognizable in that manner.
www.agron.missouri.edu/mnl/21/26Burnham.htm
Centromere-specific DNA probes for chromosomes 4, 7 and 18 were used to simultaneously analyze chromosome loss, non-disjunction, breaks within the labeled region, and nucleoplasmic bridges induced by gamma rays in binucleated human lymphocytes. ... For chromosome loss, significant increases were observed at 2 and 4 Gy,
www.medscape.com/medline/abstract/11182793
Separase, the cysteine protease that cleaves cohesin and thereby triggers chromosome disjunction, is inhibited by both securin- and phosphorylation-dependent cyclin B1 binding.
jcs.biologists.org/cgi/content/abstract/119/16/3325
Minichromosome Analysis of Chromosome Pairing, Disjunction, and Sister Chromatid Cohesion in Maize[W] ... Plant artificial chromosomes or engineered minichromosomes represent a potentially powerful research tool for understanding chromosome structure and function. Furthermore, they provide a means to assemble a collection...
www.plantcell.org/cgi/content/full/19/12/3853
Minichromosome Analysis of Chromosome Pairing, Disjunction, and Sister Chromatid Cohesion in Maize[W] ... Related articles in Plant Cell: ... This article has been cited by other articles:
www.plantcell.org/cgi/content/abstract/19/12/3853
Maternal sex chromosome non-disjunction: evidence for X chromosome-specific risk factors. ... Among the MI cases, a majority (56%) had no detectable transitions and so absent recombination is an important factor for X chromosome non-disjunction. ... Non-disjunction of chromosome 13.
www.ncbi.nlm.nih.gov/pubmed/11159943
Nondisjunction - Wikipedia, the free encyclopedia
Nondisjunction ("not coming apart") is the failure of chromosome pairs to separate properly during cell division. This could arise from a failure of homologous chromosomes to separate in meiosis I, o...
en.wikipedia.org/wiki/Nondisjunction