“Drug idiosyncrasy” refers to untoward reactions to drugs that occur in a small fraction of patients and have no obvious relationship to dose or duration of ...
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jpet.aspetjournals.org/content/307/1/1.abstract
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Sep 3, 2003 ... “Drug idiosyncrasy” refers to untoward reactions to drugs that occur in ... can explain the features of drug idiosyncrasy using fundamental ...
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jpet.aspetjournals.org/content/early/2003/09/03/jpet.10...
jpet.aspetjournals.org/content/early/2003/09/03/jpet.102.041624.full.pdf
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"Drug idiosyncrasy" refers to untoward reactions to drugs that occur in a small fraction of patients and have no obvious relationship to dose or duration of therapy. The liver is a frequent target for toxicity.
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www.medscape.com/medline/abstract/12954806
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Key Words: inflammation; drug idiosyncrasy; gene array; lipopolysaccharide; hepatotoxicity. ... Direct comparison of hepatic gene expression elicited by these two drugs might help to identify changes critical for LPS/RAN-induced liver injury and possibly RAN idiosyncrasy.
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toxsci.oxfordjournals.org/cgi/content/full/90/2/569
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and Drug Safety Evaluation, Bristol-Myers Squibb, Syracuse, New York ... They were killed 2 or 6 h after drug treatment for evaluation of hepatotoxicity (2 and 6 h) and liver gene expression (2 h only). At a time before the onset ... Key Words: inflammation; drug idiosyncrasy; gene array; lipopolysaccharide; hepatotoxicity.
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toxsci.oxfordjournals.org/cgi/content/abstract/90/2/569
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Inflammation and drug idiosyncrasy--is there a connection? ... "Drug idiosyncrasy" refers to untoward reactions to drugs that occur in a small fraction of patients and have no obvious relationship to dose or duration of therapy. The liver is a frequent target for toxicity.
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www.ncbi.nlm.nih.gov/pubmed/12954806
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drug reaction ... Adverse drug reactions ... In drug idiosyncrasy, a person’s individual genetic makeup causes an unusual reaction to the drug, often because of a lack of a particular enzyme, which is important in dealing with that drug in the body.
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www.allergy.org.nz/about+allergies/drug+reaction.html
www.allergy.org.nz/about+allergies/drug+reaction.html
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Hutchinson encyclopedia article about drug idiosyncrasy. drug idiosyncrasy. Information about drug idiosyncrasy in the Hutchinson encyclopedia. ... (redirected from drug idiosyncrasy)
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encyclopedia.farlex.com/drug+idiosyncrasy
encyclopedia.farlex.com/drug+idiosyncrasy
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1. Exposure to LPS and other inflammagens as a determinant of drug idiosyncrasy. Systemic exposure to LPS and other inflammagens is commonplace and episodic. For example, LPS exposure can occur from a locus of infection or from translocation of LPS from the intestine into the portal circulation.
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depts.washington.edu/envhlth/seminar580/pdf/speaker_pdf...
depts.washington.edu/envhlth/seminar580/pdf/speaker_pdfs/Roth.pdf
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