Proteins are gene products and so polymorphic versions are simply reflections of allelic differences in the gene; that is, allelic differences in DNA. ... All human populations are polymorphic for the prion protein PrPC. It is encoded by the prion protein gene (PRNP). Two of the alleles have different codons at position 129:
users.rcn.com/jkimball.ma.ultranet/BiologyPages/P/Polym... users.rcn.com/jkimball.ma.ultranet/BiologyPages/P/Polymorphisms.html
Single-nucleotide polymorphism - Wikipedia, the free encyclopedia
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A single-nucleotide polymorphism ( SNP , pronounced snip ) is a DNA sequence variation occurring when a single nucleotide — A, T, C, or G — in the genome (or other shared sequence) differs betwe...
en.wikipedia.org/wiki/Single-nucleotide_polymorphism
Rights-managed illustration of Normal, Mutant, and Polymorphic Gene Expression from the Netter Collection, drawn by John A. Craig ... TITLE: Normal, Mutant, and Polymorphic Gene Expression...
www.netterimages.com/image/2869.htm
Background  Many studies have investigated the association between the angiotensin-converting enzyme (ACE) gene insertion (I)/deletion (D) polymorphic variant and coronary artery disease (CAD).
archinte.ama-assn.org/cgi/content/abstract/168/10/1077
We report the identification of two novel minor histocompatibility antigens (mHAgs), encoded by two separate single nucleotide polymorphisms on a single gene, BCL2A1, and restricted by human histocompatibility leukocyte antigen (HLA)-A*2402 (the most common HLA-A allele in Japanese) and B*4403, respectively.
jem.rupress.org/cgi/content/abstract/197/11/1489
Using linkage analysis and a variety of publicly accessible databases, we have identified a polymorphic gene encoding two mHAg epitopes recognized by these CTL clones.
jem.rupress.org/cgi/content/full/197/11/1489
Although ABCC4 is a highly polymorphic gene (Saito et al., 2002 ), few data are available concerning the function of its variants. Recent studies have investigated the functional effects of several ABCC4 single-nucleotide polymorphisms (SNPs) on drug disposition.
jpet.aspetjournals.org/cgi/content/full/325/3/859
Polymorphisms in multidrug resistance-associated protein gene 4 is associated with outcome in childhood acute lymphoblastic leukemia; Blood, August 13, 2009; 114(7): 1383 - 1386. [Abstract] [Full Text] [PDF];
jpet.aspetjournals.org/cgi/content/abstract/325/3/859
A polymorphic gene is one for which the most common allele has a frequency of less than 0.95 (95%). Mammals are about 15% polymorphic.
http://www.netpets.com/dogs/healthspa/genforbreed.html
We have characterized the 5' and 3' regions of the human albumin gene with respect to nucleotide sequences, mRNA transcription initiation and polyadenylation. There are at least two transcription initiation sites and two polyadenylation sites in the human albumin gene.
www.jbc.org/cgi/content/abstract/261/7/3244