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Telomeres are important so their steady shrinking with each mitosis might impose a finite life span on cells. This, in fact, is the case. Normal (non-cancerous) cells do not grow indefinitely when placed in culture.
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users.rcn.com/jkimball.ma.ultranet/BiologyPages/T/Telom...
users.rcn.com/jkimball.ma.ultranet/BiologyPages/T/Telomeres.html
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However, they do not continue to divide indefinitely and eventually, ... Unlike primary and secondary cells, immortalized cells continue to grow and divide indefinitely in vitro for as long as the correct culture conditions are maintained. Immortalized cell lines are also known as transformed cells - i.e.
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www.microbiologybytes.com/video/culture.html
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Primary cultures contain cells that have been harvested from an animal, dissociated and plated into a culture dish. Since most differentiated cells do not continue to grow and divide indefinitely, most primary cultures do not survive for very long periods of time.
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www.williams.edu/BIMO/liz/LAB6.html
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These cells grow indefinitely in the lab and are termed pluripotent, as they can develop into any of the cell types of the body ... Adult stem cells do not grow indefinitely in the lab and, although they can be found in a great number of tissues, these special cells are generally rare and hard to identify.
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www.scu.edu/ethics/publications/submitted/stem_cells.ht...
www.scu.edu/ethics/publications/submitted/stem_cells.html
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Expression of SV40 largeT and small T oncogene leads to an extention of the lifespan of normal cells. The largeT protein binds to important cellular proteins Nevertheless transfected cells do not grow indefinitely and enter crisis. Only in rare cases clones of immortalised cells arise, growing as continous cell lines.
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www.wiley.com/legacy/products/subject/life/cytometry/is...
www.wiley.com/legacy/products/subject/life/cytometry/isac2000/6825.htm
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Once isolated, stem cells from an embryonic stem cell colony in culture cannot form an embryo6. These unspecialised embryonic stem cells can self-replicate indefinitely or under the right conditions be changed into specialized cells of the body (Fig 1). ... Why do adult stem cells not continue to grow indefinitely?
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www.tara-source.com/Features/stemscells.html
www.tara-source.com/Features/stemscells.html
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More on stem cells: Stem cells only grow up properly in the right environment ... Sickle cell mice cured by stem cells reprogrammed from their own tails « Not Exactly Rocket Science, on December 8th, 2007 at 2:08 am Said:
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notexactlyrocketscience.wordpress.com/2007/11/23/human-...
notexactlyrocketscience.wordpress.com/2007/11/23/human-skin-cells-reprogrammed-into-stem-cells/
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Most normal primary cells do not grow indefinitely in culture. ATCC immortalized cells enable you to use the same consistent material throughout a research project, without having to establish new cultures. These cells have an extended life span and maintain the genotype and phenotypic markers of the source tissue.
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www.atcc.org/CellImmortalization/tabid/658/Default.aspx
www.atcc.org/CellImmortalization/tabid/658/Default.aspx
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Virus - Wikipedia, the free encyclopedia
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A virus (from the Latin virus meaning toxin or poison ) is a microscopic infectious agent that can reproduce only inside a host cell. Viruses infect all types of organisms: from animals and pl...
en.wikipedia.org/wiki/Virus
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