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Aestivation (botany) - Wikipedia, the free encyclopedia
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Thus, cochleate preparations have the potential to delivery AMB orally. ... These results demonstrate that CAMB, a formulation of cochleate lipid particles containing AMB, promotes the uptake of AMB from the gastrointestinal tract and suggest that this route of administration has the potential for therapeutic application.
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Rosaria Santangelo,1 Padmaja Paderu,1 Guillaume Delmas,1 Zi-Wei Chen,2 Raphael Mannino,2 Leila Zarif,2 and David S. P ... Public Health Research Institute, New York, New York, 10016,1 and BioDelivery Science Inc. UMDNJ, Newark, New Jersey 071032 ... Amphotericin B (AMB) remains the principal therapeutic choice for deep mycoses.
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Cochleate structures obtained from the outer membrane of Neisseria meningitidis serotype B have demonstrated to be high immunogenicity when administrated by ...
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Enabling Platform Technology Cochleate Delivery Vehicles Stable, phospholipid-calcium precipitates Self-assembling crystalline units Multilayered structure, containing little or no internal aqueous space Resistant to degradation in GI tract Increases Processing and Shelf Life Stability Composed of naturally...
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Cochleates are lipid-based delivery system that have found application in drug and gene delivery. They are precipitates, formed as a result of interaction ...
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Herein are inital in vivo studies of a novel lipid formulation of amphotericin B - cochleate (AMBc) - named for its unique shape and characterized by excellent stability, and ability to target AMB to fungi.
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determine the structure of plain cochleates prepared 10mg/mL using ... Maintenance and possible enhancement of highly ordered cochleate lamellar structure ...
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AFCo1, a meningococcal B-derived cochleate adjuvant, strongly enhances antibody and T-cell immunity against Plasmodium falciparum merozoite surface protein ...
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We evaluated the potential of two bacterial derived compounds, Cochleate and Proteoliposome (PL), administrated to mice by nasal or oral ...
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