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Endolysin - Wikipedia, the free encyclopedia
Endolysin is a generic term describing an enzyme that degrades the bacterial peptidoglycan cell wall, resulting in lysis of the bacterial cell. At the end of the bacteriophage replication cycle, bact...
en.wikipedia.org/wiki/Endolysin
To analyze the antibacterial activity of Bacillus amyloliquefaciens phage endolysin, nine deletion derivatives of the endolysin were constructed. ...
linkinghub.elsevier.com/retrieve/pii/S001457930102587X
T7 Endolysin defined on the Free Online Medical Dictionary. Medical terminology definitions including drugs, abbreviations, equipment, devices, and more from almost all medical specialties. Online-Medical-Dictionary.org ... a free online medical dictionary search engine for definitions of medical terminology,
www.online-medical-dictionary.org/T7+Endolysin.asp?q=T7... www.online-medical-dictionary.org/T7+Endolysin.asp?q=T7+Endolysin
However, there is only one report directly comparing the activity of an endolysin with that of an antibiotic, and no general conclusions can be drawn regarding whether lysins are more effective than traditional antibiotics.
www.ebmonline.org/cgi/content/abstract/231/4/366
The intrinsic resistance of Oenococcus oeni cells to the secreted endolysin from oenophage fOg44 (Lys44) was investigated. ...
www.ncbi.nlm.nih.gov/pmc/articles/PMC2223723/
direct in vitro synthesis of X endolysin in a cell-free protein- ... by gene N. The ability to stimulate endolysin synthesis ...
www.pnas.org/content/69/12/3606.full.pdf
Mastitis is an infection of dairy cattle mammary glands. It costs the US dairy industry $2 billion dollars annually. ... The endolysin was tested and shown to maintain this lytic activity over a broad pH range, including that of milk, pH 6.7, and has a peak of activity at the free calcium concentration of milk (3mM).
www.ars.usda.gov/research/publications/publications.htm... www.ars.usda.gov/research/publications/publications.htm?seq_no_115=190308
Here, we show that bacteriophage endolysin can be used to inhibit and kill C. difficile. The genome sequence of a novel bacteriophage that is active against C. difficile was determined, and the bacteriophage endolysin gene was subcloned and expressed in Escherichia coli.
jb.asm.org/cgi/content/full/190/20/6734
Double-stranded DNA phages require two proteins for efficient host lysis: the endolysin, a muralytic enzyme, and the holin, a small membrane protein. In an event that defines the end of the vegetative cycle, the holin S acts suddenly to permeabilize the membrane.
jb.asm.org/cgi/content/full/185/3/779
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aem.asm.org/cgi/reprint/61/3/1150