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Artesunate - Wikipedia, the free encyclopedia
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Artemisinin - Wikipedia, the free encyclopedia
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Artesunate is an antimalarial agent. It is a water-soluble hemisuccinate derivative of dihydroartemisinin. Artemisinin is a sesquiterpene lactone isolated from Artemisia annua, a herb that has traditionally been used in China for the treatment of malaria.
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Artesunate is in the class of medications known as artemesinins, which are derivatives from the "quinghaosu" or sweet wormwood plant (Artemisia annua). ... A new IND now makes intravenous artesunate available to hospitals treating patients with severe malaria...
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Clinical Therapeutics from The New England Journal of Medicine -- Artesunate for the Treatment of Severe Falciparum Malaria ... Artesunate for the Treatment of Severe Falciparum Malari...
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Other POC-IT Resources ... POC-IT Center; HIV Guide; ... JH Infection Control; Center for Clinical Global Health; JH Viral Hepatitis Center; JH Center for Global Health; JH Division of Infectious Diseases; Infectious Diseases Grand Rounds; Zambia HIV Guide;
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350 children with uncomplicated P. falciparum malaria were enrolled in prospective treatment trial of mefloquine or artesunate-mefloquine between 2007 and 2008. Gametocytaemia was quantified, and gametocytes were sexed by morphological appearance, before and following treatment.
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Artesunate is a commonly used antimalarial drug derived from artemisinin. It is rapidly converted to dihydroartemisinin. Little is known on this conversion in the GI tract and blood, and how this influences absorption.
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We recently found artesunate plus sulfadoxine-pyrimethamine (ART-SP) to be highly effective (96%) in the treatment of falciparum malaria in Papua Province.
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