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V(D)J recombination
For example, the immunoglobulin heavy chain region contains 65 Variable (V) genes plus 27 Diversity (D) genes and 6 Joining (J) genes. The light chains also ... More »
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www.ncbi.nlm.nih.gov/pmc/articles/PMC391569/
In order to assess whether DNA rearrangement occurs with equal frequency at each of the several J (joining region) elements in the mouse kappa light chain ...
www.ncbi.nlm.nih.gov/pmc/articles/PMC390723/
Using this cleavage site, we were able to assess the relative recombination frequency of the kappa chain joining region gene (J kappa) segments in mouse ...
www.pnas.org/content/81/15/4756.full.pdf
Different joining region J elements of the murine K immunoglobulin light chain locus are used at markedly different frequencies. (inimunoglobulin genes/joining ...
www.ncbi.nlm.nih.gov/pubmed/3931074
Preferential rearrangement of the immunoglobulin kappa chain joining region J kappa 1 and J kappa 2 segments in mouse spleen DNA. Nishi M, Kataoka T, ...
www.microbiologytext.com/index.php?module=Book&func=dis... www.microbiologytext.com/index.php?module=Book&func=displayarticle&art_id=394
Light chain antibody regions consist of a constant region (C), a joining region (J) and a variable region (V). During the differentiation of the B cell, a deletion joins ...
www.jstor.org/stable/23989
DifFerent joining region J elements of the murine ic immunoglobulin light chain locus are used at markedly different frequencies. (immunoglobulin genes/joining ...
pathmicro.med.sc.edu/mayer/iggenetics2000.htm
Jul 15, 2010 ... J region. D region. Leader Enhancer Promotor Antibody diversity ... of each of the C genes there is and additional exon called J (joining). The L ...
www.jimmunol.org/content/138/8/2687.full.pdf
the variable joining (VJ)" junction (5-7, 9, 12, 14, 17). Here we present evidence for greater germline J region diversity than previously suspected. We have ...
faculty.ccbcmd.edu/courses/bio141/lecguide/unit5/humora... faculty.ccbcmd.edu/courses/bio141/lecguide/unit5/humoral/abydiversity/vdj_flash.html
joining region genes (5 for kappa chain). constant region gene for kappa chain. Through a process of chromosomal looping and the action of V(D)J recombinase ...
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