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Metiamide - Wikipedia, the free encyclopedia
Metiamide is a histamine H 2 -receptor antagonist developed from another H 2 antagonist, burimamide. It was an intermediate compound in the development of the successful anti-ulcer drug cimetidin...
en.wikipedia.org/wiki/Metiamide |
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File; File history; File links. File:Metiamide.png. Size of this preview: 800 × 318 pixels ... Description: Skeletal formula of metiamide ...
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an antihistamine drug C9H16N4S2 that has been used experimentally in the treatment of peptic ulcers. Bing Learn more about "METIAMIDE" ...
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802) stated that doubleblind clinical trials had shown metiamide, a histamine H2receptor antagonist, to have significantly and beneficially affected pain ...
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In a multicentre double-blind trial 68 patients with endoscopically confirmed duodenal ulceration received metiamide (36 patients) or placebo (32 patients) ...
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Definition of metiamide from the online medical dictionary hosted by mondofacto.
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Development of metiamide from burimamide ... Modification of metiamide to cimetidine ... in clinical trials, an unacceptable number of patients dosed with metiamide developed agranulocytosis...
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The effects of the histamine H2-receptor inhibitor metiamide on histamine-stimulated canine bile flow and gastric hydrogen ion output were evaluated. Histamine was found to stimulate bile volume in doses comparable to those that stimulated gastric hydrogen ion output;
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1. The action of metiamide, a specific histamine H2-receptor antagonist, on the acid secretory response to various gastric stimuli in the perfused isolated whole mouse stomach is described. 2. Two kinds of stomach preparations, the non-distended stomach and distended stomach, were used.
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Because of evidence that Metiamide, an H2-receptor antagonist, strongly inhibits gastric acid secretion, the present study was designed to test the hypothesis that Metiamide will prevent bile salt-induced stress ulcers during hemorrhagic shock. ... 34839-70-8 (Metiamide)
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